Do health workers' preferences influence their practices? Assessment of providers' attitude and personal use of new treatment recommendations for... (Publications)
suitable for the management of uncomplicated malaria for the three patient categories: i) children below 5; ii) older children and adults; and iii) pregnant women. Practice was ascertained by asking which a
Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage rhodesiense sleeping sickness (Publications)
follow-up after 3, 6 and 12 months. RESULTS: The incidence of ES in the trial population was 11.2% (CI 5-17%) and 13% (CI 9-17%) in the historic data. The respective case fatality rates were 8.4% (CI 3-13
A research agenda for malaria eradication: modeling (Publications)
achieving a set of goals in different socio-ecological settings and different health systems; and (5) operational feasibility assessments to weigh the economic costs, capital investments, and human resource
Prevalence of cardiovascular risk factors in the Basel city population 1989-1990 (Publications)
Hg) is observed in 17% of the men and 12% of the women, whereas an elevated cholesterol level (over 6.5 mmol/l) concerns respectively 39% and 28% of them. Regular cigarette smokers represent 30% of the males
Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent... (Publications)
BOX-PCR and MLST. RESULTS: Twenty-nine different serotypes were identified; serotypes 14, 19A, 12F, 5, 23F, and 1 were common and accounted for 58.3% of all serotypes overall. MLST analysis showed 72 sequence
The extended AT-hook is a novel RNA binding motif (Publications)
identified 80 human and 60 mouse eAT-hook proteins and biochemically characterized the eAT-hooks of Tip5/BAZ2A, PTOV1 and GPBP1. Microscale thermophoresis and electrophoretic mobility shift assays reveal the
MMP-1 and -3 promoter variants are indicative of a common susceptibility for skin and lung aging: results from a cohort of elderly women (SALIA) (Publications)
(MMP-1) 2G (rs1799750) or the MMP-3 6A (rs3025058) allele but not in homozygous carriers of the 1G or 5A allele. Thus, skin and lung aging are linked in carriers of the 2G or 6A allele. These alleles appear
Measurements of particle number and mass concentrations and size distributions in a tunnel environment (Publications)
occasional smaller modes around 100 nm. The PM10 mass emission factor for heavy-duty vehicles was 14.5 times higher than that of light-duty vehicles. The particles derived from diesel are more abundant in
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence... (Publications)
LiN[Si(CH(3))(3)](2) or by Pinner methodology. Specifically, we have prepared new series of 2,6- and 2,5-diaryl indoles (6a,b, 12 and 17a-d) and the related benzimidazoles (24, 30 and 35). The new compounds
Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives (Publications)
optimization study based on the lead antitrypanosomal compound 1,2-dihydro-2,2,4-trimethylquinolin-6-yl 3,5-dimethoxybenzoate (TDR20364, 1a) was undertaken in an attempt to discover new trypanocides with potent