Prevalence of cardiovascular risk factors in the Basel city population 1989-1990 (Publications)
Hg) is observed in 17% of the men and 12% of the women, whereas an elevated cholesterol level (over 6.5 mmol/l) concerns respectively 39% and 28% of them. Regular cigarette smokers represent 30% of the males
Real-time PCR detection and quantification of vector trichodorid nematodes and <em>Tobacco rattle virus</em> (Publications)
r trichodorid nematodes and associated Tobacco rattle virus (TRV) based on a real-time fluorogenic 5' nuclease PCR assay (TaqMan). Two independent primer/probe sets were designed targeting the 18S gene
Determinants of change in airway reactivity over 11 years in a population study (SAPALDIA) (Publications)
its maximal value per mumol methacholine. Bronchial hyper-reactivity prevalence fell from 14.3% to 12.5% during follow-up. Baseline age was non-linearly associated to change in reactivity slope: participants
Drug-induced differential culturability in diverse strains of <em>Mycobacterium tuberculosis</em> (Publications)
Mtb-positive cultures in liquid as opposed to solid medium, with this liquid culture bias extending up to 5 months post diagnosis. Experimentally, there was a disparity between bacterial time to positivity (TTP)
Sex-specific associations of cardiovascular risk factors with carotid stiffness - results from the SAPALDIA cohort study (Publications)
per 1SD of the risk factor on an inverted scale) and significant adverse risk factors were BMI (-0.5; 4.7%), systolic (-1.23; 4.7%) and diastolic blood pressure (1.4; 4.4%), heart rate (2.7; 7.9%), C-reactive
A multiplex qPCR approach for detection of <em>pfhrp2 </em>and <em>pfhrp3</em> gene deletions in multiple strain infections of <em>Plasmodium... (Publications)
pfhrp2 and pfhrp3 deletion status correctly in 93.4% of samples with parasitemia levels higher than 5 parasites/µL when compared to nested PCR. The qHRP2/3-del assay can correctly identify pfhrp2 and pfhrp3
Care-seeking dynamics among patients with diabetes mellitus and hypertension in selected rural settings in Kenya (Publications)
hypertension through face-to-face interviews. Of the 1100 participants, 69.9% had hypertension, 15.5% diabetes while 14.7% had both. The mean age of the respondents was 64 years. The majority of the r
Limited genetic diversity of hepatitis B virus in the general population of the Offin River valley in Ghana (Publications)
countries, the other 33 formed a separate cluster distinguished by an intergroup mean distance of 1.5% from the pan-African HBV/E cluster. Successful implementation of HBV vaccination in the region was
Somatic mutation footprinting reveals a unique tetra-nucleotide signature associated with intron-exon boundaries in lung cancer (Publications)
level and intron-exon junctions. Intriguingly, its distribution across the genome is biased towards 5' splice junctions, suggesting a novel mechanism of mutation.
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (Publications)
structural variants were identified, including 99% of low-frequency (minor allele frequency [MAF] 0.1-5%) non-coding variants in the whole-genome sequenced individuals and 99.7% of low-frequency coding variants