Measuring early childhood development in Brazil: validation of the Caregiver Reported Early Development Instruments (CREDI) (Publications)
consistency/inter-item reliability (alpha> 0.80) for the CREDI within each of the six age groups (0-5, 6-11, 12-17, 18-23, 24-29 and 30-35 months of age). Multivariate analyses of construct validity showed
Development of a pharmacovigilance system in a resource-limited country: the experience of the Democratic Republic of Congo (Publications)
the health system; (3) data collection and analysis; (4) collaboration with public health programs; (5) collaboration with the National Regulatory Authority. Lessons learnt from the DRC experience show that
Short course amphotericin B in addition to sertraline and fluconazole for treatment of HIV-associated cryptococcal meningitis in rural Tanzania (Publications)
sertraline 400 mg/day and fluconazole 1200 mg/day (n=28) vs. sertraline, fluconazole and additional 5-days of amphotericin B deoxycholate 0.7-1 mg/kg (n=18) for cryptococcal meningitis. RESULTS: 2-week
Dog ecology, bite incidence, and disease awareness: a cross-sectional survey among a rabies-affected community in the Democratic Republic of the Congo (Publications)
officials, with a large proportion of free-roaming unvaccinated dogs. The annual dog bite incidence of 5.2 per 1000 person years was high, whereas community rabies knowledge was low resulting in poor practices
Rapid diagnosis of bacterial meningitis by real-time PCR and fluorescence in situ hybridization (Publications)
discordant results by culture and microscopy were successfully investigated by PCR (10 samples) and FISH (5 samples). In conclusion, PCR is a highly sensitive tool for rapid diagnosis of bacterial meningitis
Marginal bone loss one year after implantation: a systematic review of different loading protocols (Publications)
loaded implants (0.05+/-0.67mm) and the highest for immediate non-occlusally loaded implants (1.37+/-0.5mm). The results of the meta-analysis showed an estimated mean MBL of 0.457mm (95% confidence interval
Human monocytotropic ehrlichiosis - a systematic review and analysis of the literature (Publications)
(9.9%) and immunocompromized (16.3%) cases, and sequelae are rare (4.2% in immunocompetent cases, 2.5% in immunocompromised cases).
Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool (Publications)
At baseline FECPAKG2 revealed a sensitivity of 75.6% (72.0-77.7) for detecting A. lumbricoides, 71.5% (67.4-95.3) for hookworm and 65.8% (64.9-66.2) for T. trichiura, which was significantly lower (all
Life cycle maintenance and drug-sensitivity assays for early drug discovery in <em>Schistosoma mansoni</em> (Publications)
along the drug-screening cascade are also described. In these assays, which can be performed within 5 d, the effect of a drug is determined by phenotypic assessment of the parasites' viability and morphology
Anti-inflammatory and quinone reductase-inducing compounds from <em>Beilschmiedia mannii</em> (Publications)
1: and 2: were the most active. The concentrations to double the quinone reductase activity were 7.5 microM for compound 1: and 6.1 microM for compound 2: . Compounds 1: and 2: inhibited nuclear factor-kappa