Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale (Publications)
significantly affect L-PZQ exposure in both studies. The model for AUC was then extrapolated to children 2-5 years old accounting for enzyme maturation and weight. The predicted exposures were compared to an external
Sensitivity of the point-of-care circulating cathodic antigen urine cassette test for diagnosis of <em>Schistosoma mansoni</em> in low-endemicity... (Publications)
haematobium were found in eight participants (1.2%), whereas the prevalence of microhematuria was 13.5%. A single POC-CCA urine cassette test revealed a several-fold higher prevalence of S. mansoni than
Streaming data from a smartphone application: a new approach to mapping health during travel (Publications)
were centred in Bangkok. The odds of a health event were higher in Chiang Mai (2.34, 95% CI: 1.08, 5.08) and on rainy days (1.86, 95% CI: 1.03, 3.36). CONCLUSIONS: Distinct patterns in spatial and env
Tuberculosis transmission in public locations in Tanzania: a novel approach to studying airborne disease transmission (Publications)
in public transport. Lower transmission risks were found in central markets (4.8% for traders, but 0.5% for their customers), passengers on public transport (2.4%), public schools (4.0%), nightclubs (1.7%)
Land use regression modeling of outdoor noise exposure in informal settlements in Western Cape, South Africa (Publications)
dB(A)), during night (22:00-6:00) 52.9 dB(A) (49.3-55.8 dB(A)) and average Lden was 63.0 dB(A) (60.1-66.5 dB(A)). Main predictors of the LUR model were related to road traffic and household density. Model
Sustained malaria control over an 8-year period in Papua New Guinea: the challenge of low-density asymptomatic <em>Plasmodium</em> infections (Publications)
decreased from 42% in 2006 to 13% in 2010 but then increased to 20% in 2014. Parasite densities decreased 5-fold from 2006 to 2010; 72% of P. falciparum and 87% of P. vivax infections were submicroscopic in 2014
Detection of second line drug resistance among drug resistant <em>Mycobacterium tuberculosis</em> isolates in Botswana (Publications)
isolates analyzed, 33 (58%) were MDR-TB, 4 (7%) were additionally resistant to flouroquinolones and 3 (5%) were resistant to both fluoroquinolones and second-line injectable drugs. The most common fluoroquinolone
Quantification of annual settlement growth in rural mining areas using machine learning (Publications)
and temporal consistency correction. Overall accuracy in the four studied scenes ranged between 58.5% and 95.1%. Arid conditions and limited availability of Google Earth imagery negatively affected cl
Immune system development varies according to age, location, and anemia in African children (Publications)
this at-risk population. We sought to identify factors that shape immune development in children under 5 years of age from Tanzania and Mozambique by detailed immunophenotyping of longitudinal blood samples
Fluorescence in situ hybridization (FISH) for rapid identification of <em>Salmonella</em> spp. from agar and blood culture broth--an option for the... (Publications)
of 97.4% for environmental Salmonella spp. isolates, and sensitivity of 100% and specificity of 99.5% for blood culture materials. CONCLUSIONS: FISH proved to be highly reliable for a rapid identification