Culture and psychiatric evaluation: operationalizing cultural formulation for DSM-5 (Publications)
guidance on implementation, training, and application in diverse settings. To address this need, DSM-5 introduced a cultural formulation interview (CFI) that operationalizes the process of data collection [...] article summarizes the literature reviews and analyses of experience with the OCF conducted by the DSM-5 Cross-Cultural Issues Subgroup (DCCIS) that informed the development of the CFI. We review the history
National and sub-national exposure to ambient fine particulate matter PM2.5 and its attributable burden of disease in Iran from 1990 to 2016 (Publications)
Ambient particulate matter is a public health concern. We aimed (1) to estimate national and provincial long-term exposure of Iranians to ambient particulate matter (PM)
O-5S quantitative real-time PCR: a new diagnostic tool for laboratory confirmation of human onchocerciasis (Publications)
microscopy, O-150 qPCR, and the novel O-5S qPCR. RESULTS: Among the 200 individuals, 133 patients tested positive (positivity rate of 66.5%) and 67 negative by O-5S qPCR, 74 tested positive by microscopy [...] individuals who tested negative by O-5S qPCR tested positive by microscopy or O-150 qPCR, implying 100% specificity of the newly designed O-5S qPCR assay. CONCLUSIONS: The novel O-5S qPCR assay is more sensitive [...] qPCR (39.0%). Among the 133 O-5S qPCR positive individuals, microscopy...
Feasibility of caregiver-administered anthropometric measurements of children under age 5: evidence from Zambia (Publications)
feasibility and reliability of caregiver-administered anthropometric assessments of children under age 5. DESIGN: We compared standard and caregiver-administered assessments within an ongoing nutrition trial
Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from... (Publications)
the Chinese liana Ancistrocladus tectorius (Ancistrocladaceae), two new 5,8'-coupled naphthylisoquinolines, ancistectorine D (5) and its 6-O-demethyl derivative 6, were isolated, along with two new 7,1'-linked [...] (oxidative degradation) and chiroptical (circular dichroism) methods. Chemotaxonomically remarkable, 5,8'-coupled naphthylisoquinolines have as yet been found quite rarely in Asian Ancistrocladus species [...] coupling type represent the by far the largest group of constituents in...
Spatial PM2.5, NO2, O3 and BC models for Western Europe - evaluation of spatiotemporal stability (Publications)
health relevant air pollutants (PM2.5, NO2, BC, O3) across Europe. METHODS: We developed West-European land use regression models (LUR) for 2010 estimating annual mean PM2.5, NO2, BC and O3 concentrations [...] time, separate models were developed for different years (NO2 and O3: 2000 and 2005; PM2.5: 2013). RESULTS: The PM2.5, BC, NO2, O3 annual, O3 warm season and O3 cold season models explained respectively 72% [...] and 16% of the R(2) in the PM2.5, O3 warm and O3 cold models. Explained...
Immunologic-based diagnosis of latent tuberculosis among children less than 5 years of age exposed and unexposed to tuberculosis in Tanzania:... (Publications)
those with and without exposure: 20% (38/186) vs. 20% (23/115) QFT-positive, and 2% (4/186) vs. 4% (5/115) indeterminate QFT. QFT conversion rate was 7% (22 children) and reversion 8% (25 children). Of
Comparative genomics of <em>Mycobacterium africanum</em> lineage 5 and lineage 6 from Ghana suggests distinct ecological niches (Publications)
Lineage 5 (L5) and N = 78 Lineage 6 (L6). We found that the genomic diversity of L6 was higher than in L5 despite the smaller sample size. Regulatory proteins appeared to evolve neutrally in L5 but under [...] epitopes overall compared to L5. Of the 10% human T cell epitopes that were variable, most carried mutations that were lineage-specific. Our findings indicate that Maf L5 and L6 differ in some of their
Hourly land-use regression modeling for NO2 and PM2.5 in the Netherlands (Publications)
performed overall well (5-fold cross validation R(2) = 0.50 - 0.78), while the PM(2.5) performed moderately (5-fold cross validation R(2) = 0.24 - 0.62). Both for NO(2) and PM(2.5) the warm season models [...] this study we aimed to model average hourly concentrations for two major pollutants, NO(2) and PM(2.5), for the Netherlands using the LUR algorithm. We modelled the spatial variation of average hourly [...] models performed overall worse than both modelling approaches (NO(2) hourly R(2) =...
Association between concurrence of multiple risk factors and under-5 mortality: a pooled analysis of data from demographic and health survey in 61... (Publications)
al strategies to address preventable under-5 mortality (U5M). This study aims to assess the associations between concurrence of multiple risk factors and U5M in LMICs. METHODS: We extracted data from the [...] 61 LMICs. Our primary outcome was U5M, defined as deaths from birth to 59 months. Binary logistic regression model was applied to ascertain the association between U5M and a total of 20 critical risk factors [...] factors in each individual and assessed their combined effects on U5M with...