Clonal waves of <em>Neisseria</em> colonisation and disease in the African meningitis belt: eight- year longitudinal study in Northern Ghana (Publications)
carriage isolates were associated with three sequential waves of colonisation with encapsulated (A ST5, X ST751, and A ST7) meningococci. Compared to industrialised countries, the colonising meningococcal
Use of whole genome sequencing to determine the microevolution of <em>Mycobacterium tuberculosis</em> during an outbreak (Publications)
polymorphisms data confirmed all except one known epidemiological link. The outbreak strain resulted in 5 bacterial variants originating from the index case A1 with 0-2 mutations per transmission event that
Risk of latent tuberculosis infection in children living in households with tuberculosis patients: a cross sectional survey in remote northern Lao... (Publications)
sputum prior to treatment (AFB > 2+; OR: 4.7, 95% CI: 1.7-12.3), and living in ethnic minorities (OR: 5.4, 95% CI: 2.2-13.6). CONCLUSION: The study supports the importance of contact tracing in remote settings
Costs and effects of the Tanzanian national voucher scheme for insecticide-treated nets (Publications)
and death averted.RESULTS AND CONCLUSION:The total financial cost of the programme represents around 5% of the Ministry of Health's total budget. The average economic cost of delivering an ITN using the
Short Message Service (SMS) applications for disease prevention in developing countries (Publications)
prevention in developing countries. RESULTS: A total of 34 SMS applications were described, among which 5 had findings of an evaluation reported. The majority of SMS applications were pilot projects in various
Urban agriculture and <em>Anopheles</em> habitats in Dar es Salaam, Tanzania (Publications)
using multivariate logistic regression with independent random effects. It was found that more than 5% of the study area (total size 16.8 km2) was used for farming in backyard gardens and larger open spaces
<em>Plasmodium falciparum</em>: cloned and expressed CIDR domains of PfEMP1 bind to chondroitin sulfate A (Publications)
binding using soluble CSA inhibited binding to CHO cells by up to 100% at 2 mg/ml and by 62.4% at 0.5 mg/ml, whereas 1 mg/ml heparan sulfate had only a little effect (18.1%). In contrast, a recombinant
Prevalence of clinically significant functional fatigue or weakness in specialty outpatient clinics of Pune, India (Publications)
sexes, and to compute rates adjusted for age, sex, and the clinic attended. Overall prevalence was 5.02% with higher rates in the dermatology and ayurved clinics than in psychiatry and medicine clinics
The procyclin-associated genes of <em>Trypanosoma brucei</em> are not essential for cyclical transmission by tsetse (Publications)
we show that the EP/PAG1 locus in AnTat1.1 has to be extended by three more PAGs, which we named PAG5, PAG2* and PAG4. The EP/PAG2 locus most likely evolved from the EP/PAG1 locus by deletion of a fragment
<em>Trypanosoma congolense</em> procyclins: unmasking cryptic major surface glycoproteins in procyclic forms (Publications)
The protein is densely N glycosylated, with up to 13 high-mannose oligosaccharides ranging from Man(5)GlcNAc(2) to Man(9)GlcNAc(2) linked to the peptide repeats. The lipid moiety of the glycosylphospha