Gene-environment interaction for childhood asthma and exposure to farming in Central Europe (Publications)
and 7 SNPs that emerged as genome-wide significant in a large meta-analysis of childhood asthma and 5 SNPs that had been reported previously as interacting with farm exposures for asthma or atopy. RESULTS:
An individual-based model of <em>Plasmodium falciparum</em> malaria transmission on the coast of Kenya (Publications)
transmission was stable even in low transmission areas where the human-biting rate is approximately 0.5 bite per day. The model was used to examine the effect of infection control programmes that aim at
Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study (Publications)
MEASURES: Prognostic indicators of mortality. RESULTS: Of 8091 children admitted up to 1 June 2000, 436 (5%) died. Sixty (14%) died within four hours after admission (immediate), 193 (44%) after 4-48 hours (early)
Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis) (Publications)
consistent with heart failure such as exertional dyspnoea (19%vs. 1.7%; P = 0.002) or palpitations (18%vs. 5%; P = 0.28) occurred more frequently in patients than in controls. The median NT-proBNP was significantly
The procyclin-associated genes of <em>Trypanosoma brucei</em> are not essential for cyclical transmission by tsetse (Publications)
we show that the EP/PAG1 locus in AnTat1.1 has to be extended by three more PAGs, which we named PAG5, PAG2* and PAG4. The EP/PAG2 locus most likely evolved from the EP/PAG1 locus by deletion of a fragment
Prevalence of clinically significant functional fatigue or weakness in specialty outpatient clinics of Pune, India (Publications)
sexes, and to compute rates adjusted for age, sex, and the clinic attended. Overall prevalence was 5.02% with higher rates in the dermatology and ayurved clinics than in psychiatry and medicine clinics
<em>Trypanosoma congolense</em> procyclins: unmasking cryptic major surface glycoproteins in procyclic forms (Publications)
The protein is densely N glycosylated, with up to 13 high-mannose oligosaccharides ranging from Man(5)GlcNAc(2) to Man(9)GlcNAc(2) linked to the peptide repeats. The lipid moiety of the glycosylphospha
Clonal waves of <em>Neisseria</em> colonisation and disease in the African meningitis belt: eight- year longitudinal study in Northern Ghana (Publications)
carriage isolates were associated with three sequential waves of colonisation with encapsulated (A ST5, X ST751, and A ST7) meningococci. Compared to industrialised countries, the colonising meningococcal
Use of whole genome sequencing to determine the microevolution of <em>Mycobacterium tuberculosis</em> during an outbreak (Publications)
polymorphisms data confirmed all except one known epidemiological link. The outbreak strain resulted in 5 bacterial variants originating from the index case A1 with 0-2 mutations per transmission event that
Evaluating double-duty actions in Rwanda's secondary cities (Publications)
urbanizing areas. The 2019-2020 Rwanda Demographic Health Survey (DHS) revealed that 33% of children under 5 years old are stunted while 42% of women in urban areas are overweight or obese. This coexistence has