Searched for 5.

1. Exposure assessment of particulate matter for susceptible populations in Seattle (Publications)

   Exposure assessment of particulate matter for susceptible populations in Seattle

   Relevance:

   aerodynamic diameters < 2.5 microm (PM2.5) were similar to the average outdoor PM2.5 concentrations but significantly higher than the average indoor concentrations. Personal PM2.5 exposures in our study groups [...] panel studies of susceptible populations. Indoor and outdoor PM2.5, PM10 (PM with aerodynamic diameters < 10 microm), and the ratio of PM2.5 to PM10 were significantly higher during the heating season. The [...] outdoor PM10 in winter was primarily due to an increase in the PM2.5...

2. Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan... (Publications)

   Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan infants

   Relevance:

   identical MNP but with 5 mg iron (2.5 mg as sodium iron ethylenediaminetetraacetate and 2.5 mg as ferrous fumarate) (Fe group); or (3) the identical MNP as the Fe group but with 7.5 g GOS (FeGOS group). [...] (GOS) combined with a low dose (5 mg/day) of highly bioavailable iron. DESIGN: In a 4-month, controlled, double-blind trial, we randomised Kenyan infants aged 6.5-9.5 months (n=155) to receive daily (1) [...] micronutrient powders (MNPs) reduce anaemia in African infants, but the current...

3. Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan... (Publications)

   Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan infants

   Relevance:

   identical MNP but with 5 mg iron (2.5 mg as sodium iron ethylenediaminetetraacetate and 2.5 mg as ferrous fumarate) (Fe group); or (3) the identical MNP as the Fe group but with 7.5 g GOS (FeGOS group). [...] (GOS) combined with a low dose (5 mg/day) of highly bioavailable iron. DESIGN: In a 4-month, controlled, double-blind trial, we randomised Kenyan infants aged 6.5-9.5 months (n=155) to receive daily (1) [...] micronutrient powders (MNPs) reduce anaemia in African infants, but the current...

4. Exposure to non-microbial N-Glycolylneuraminic acid protects farmers' children against airway inflammation and colitis (Publications)

   Exposure to non-microbial N-Glycolylneuraminic acid protects farmers' children against airway inflammation and colitis

   Relevance:

   such as the sialic acid N-Glycolylneuraminic acid (Neu5Gc) may play a significant role. METHODS: Exposure to Neu5Gc was evaluated by quantifying anti-Neu5Gc antibody levels in the sera of children enrolled [...] (n=734), 4.5 years (n=700) and 6 years (n=728)), and we associated them with asthma and wheeze. The effect of Neu5Gc was examined in murine airway inflammation and colitis models and the role of Neu5Gc in [...] in non-atopic subjects. Exposure to Neu5Gc in mice resulted in reduced...

5. Ambient air pollution and atherosclerosis in Los Angeles (Publications)

   Ambient air pollution and atherosclerosis in Los Angeles

   Relevance:

   ions of ambient PM2.5. Exposure values were assigned from a PM2.5 surface derived from a geostatistical model. Individually assigned annual mean PM2.5 concentrations ranged from 5.2 to 26.9 microg/m3 (mean [...] association between atherosclerosis and long-term exposure to ambient PM up to 2.5 microm in aerodynamic diameter (PM2.5). Baseline data included assessment of the carotid intima-media thickness (CIMT) [...] (mean, 20.3). For a cross-sectional exposure contrast of 10 microg/m3 PM2.5,...

6. Exposure to non-microbial N-Glycolylneuraminic acid protects farmers' children against airway inflammation and colitis (Publications)

   Exposure to non-microbial N-Glycolylneuraminic acid protects farmers' children against airway inflammation and colitis

   Relevance:

   such as the sialic acid N-Glycolylneuraminic acid (Neu5Gc) may play a significant role. METHODS: Exposure to Neu5Gc was evaluated by quantifying anti-Neu5Gc antibody levels in the sera of children enrolled [...] (n=734), 4.5 years (n=700) and 6 years (n=728)), and we associated them with asthma and wheeze. The effect of Neu5Gc was examined in murine airway inflammation and colitis models and the role of Neu5Gc in [...] in non-atopic subjects. Exposure to Neu5Gc in mice resulted in reduced...

7. Ambient air pollution and atherosclerosis in Los Angeles (Publications)

   Ambient air pollution and atherosclerosis in Los Angeles

   Relevance:

   ions of ambient PM2.5. Exposure values were assigned from a PM2.5 surface derived from a geostatistical model. Individually assigned annual mean PM2.5 concentrations ranged from 5.2 to 26.9 microg/m3 (mean [...] association between atherosclerosis and long-term exposure to ambient PM up to 2.5 microm in aerodynamic diameter (PM2.5). Baseline data included assessment of the carotid intima-media thickness (CIMT) [...] (mean, 20.3). For a cross-sectional exposure contrast of 10 microg/m3 PM2.5,...

8. Marine natural products from the Turkish sponge <em>Agelas oroides</em> that inhibit the enoyl reductases from <em>Plasmodium falciparum</em>,<em>... (Publications)

   Marine natural products from the Turkish sponge <em>Agelas oroides</em> that inhibit the enoyl reductases from <em>Plasmodium falciparum</em>,<em> Mycobacterium tuberculosis</em> and <em>Escherichia coli</em>

   Relevance:

   consisting of a 1:2 mixture of (5Z,9Z)-5,9-tricosadienoic (7) and (5Z,9Z)-5,9-tetracosadienoic (8) acids, and FAMB composed of 8, (5Z,9Z)-5,9-pentacosadienoic (9) and (5Z,9Z)-5,9-hexacosadienoic (10) acids [...] cholest-5alpha-7-en-3-beta-ol (1), 4,5-dibromopyrrole-2-carboxylic acid methyl ester (2), 4,5-dibromopyrrole-2-carboxylic acid (3), (E)-oroidin (4), 3-amino-1-(2-aminoimidazoyl)-prop-1-ene (5), taurine [...] microM) than the (E)-oroidin TFA salt (4b), the active and major component of...

9. Marine natural products from the Turkish sponge <em>Agelas oroides</em> that inhibit the enoyl reductases from <em>Plasmodium falciparum</em>,<em>... (Publications)

   Marine natural products from the Turkish sponge <em>Agelas oroides</em> that inhibit the enoyl reductases from <em>Plasmodium falciparum</em>,<em> Mycobacterium tuberculosis</em> and <em>Escherichia coli</em>

   Relevance:

   consisting of a 1:2 mixture of (5Z,9Z)-5,9-tricosadienoic (7) and (5Z,9Z)-5,9-tetracosadienoic (8) acids, and FAMB composed of 8, (5Z,9Z)-5,9-pentacosadienoic (9) and (5Z,9Z)-5,9-hexacosadienoic (10) acids [...] cholest-5alpha-7-en-3-beta-ol (1), 4,5-dibromopyrrole-2-carboxylic acid methyl ester (2), 4,5-dibromopyrrole-2-carboxylic acid (3), (E)-oroidin (4), 3-amino-1-(2-aminoimidazoyl)-prop-1-ene (5), taurine [...] microM) than the (E)-oroidin TFA salt (4b), the active and major component of...

10. Spatial and sector-specific contributions of emissions to ambient air pollution and mortality in European cities: a health impact assessment (Publications)

    Spatial and sector-specific contributions of emissions to ambient air pollution and mortality in European cities: a health impact assessment

    Relevance:

    by industry (13·8% [6·0]), transport (13·5% [5·8]), energy (10·0% [6·4]), and shipping (5·5% [5·7]). For NO2, the main contributor to mortality was transport (48·5% [SD 15·2]), with additional contributions [...] energy (14·7% [12·9]), residential (10·3% [5·0]), and shipping (9·7% [12·7]). The mean city contribution to its own air pollution mortality was 13·5% (SD 9·9) for PM2·5 and 34·4% (19·6) for NO2, and contribution [...] increased among cities of largest area (22·3% [12·2] for PM2·5 and...