Core Malaria Modelling (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/core-malaria-modelling
model-based evidence informing decisions for malaria control and elimination strategies of the next 5 years and for longer term planning. Primary outcome 3: Increased quality of model-based evidence, supporting
Basic Malaria Research (Page)
https://www.swisstph.ch/en/topics/malaria/basic-malaria-research
of the P. falciparum Cysteine Rich Protective Antigen (PfCyRPA). The protein forms together with PfRH5 and PfRipr a multiprotein complex crucial for erythrocyte invasion. We have determined the crystal structure [...] falciparum schizonts is regulated by GDV1 but may not be linked to sexual commitment. mBio . 2024;15(5):e0314023. DOI: 10.1128/mbio.03140-23 Hellingman A et al. Next generation chemiluminescent probes for
Chronic Diseases Clinic Ifakara (Page)
https://www.swisstph.ch/en/projects/the-ifakara-clinic-platform/intermediate-care
Francis Referral Hospital in Ifakara, Tanzania, serves as a referral centre for a rural population of ~1.5 million people. Its Emergency Department (ED) sees 88,000 patients a year, 10% of whom are in a serious [...] system between these units, a rapid diagnosis and treament of stroke patients presenting within 4.5 hours of the onset of symptoms, and the patient relatives' visits. Implementation of Equipment Several
The Virulence-Transmission Trade-Off: Exploring the Biological Determinants and Epidemiological Consequences of Subclinical Tuberculosis (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/the-virulence-transmission-trade-off-exploring-the-biological-determinants-and-epidemiological-consequences-of-subclinical-tuberculosis
Human tuberculosis (TB) remains a global health emergency, causing 10 million new cases and 1.5 million deaths every year. TB manifests as a spectrum, ranging from self-cured or asymptomatic infection [...] caused by nine phylogenetic lineages (L1-L9) of the Mycobacterium tuberculosis Complex (MTBC). L1, L5 and L6 (also known as “ancient”) have repeatedly been associated with lower virulence in model systems
Heat effects on mortality in 15 European cities (Publications)
apparent temperature above the city-specific threshold was 3.12% (95% credibility interval = 0.60% to 5.72%) in the Mediterranean region and 1.84% (0.06% to 3.64%) in the north-continental region. Stronger
The contribution of livestock to urban resilience: the case of Bamako, Mali (Publications)
these figures, the city-wide urban livestock total gross margin for Bamako in 2010 was estimated at USD 5.6 million. Detailed population data help clarify the urban livestock animal human interface in diverse
Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis (Publications)
schistosomiasis endemic regions and freshwater contacts, an episode of fever (body temperature > /=38.5 degrees C) and an absolute or relative eosinophil count of > /=700/mul or 10%, were eligible for pa
Ambient pollen exposure and pollen allergy symptom severity in the EPOCHAL study (Publications)
exposure threshold, below which no symptoms occur. While recent pollen exposure in the last approximately 5 h affected symptoms most, associations lingered for up to 60 h. Grass pollen exposure (compared to tree
Stoma associated complications after diverting loop ileostomy, end ileostomy or split stoma formation after right sided colectomy-a retrospective... (Publications)
(65%) in PA, 7 (24%) in ES, and 29 (43%) in SS group achieved stoma closure (P = 0.02). A total of 5 patients (38%) in PA group, 2 (15%) in ES, and 22 patients (67%) in SS group had a stoma-associated
A pilot of a chronic disease self-management programme in Moldova (Publications)
participants’ self-efficacy significantly increase between baseline and follow-up (from mean score of 5.3 to 8.3; t(58) = -12.2, p < 0.001), they also improved their knowledge on every individual item on