In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species (Publications)
resulted in a maximum total worm burden reduction of 52.2%. High worm burden reductions (71.7 to 86.5%) were observed after administration of single 200-mg/kg doses of OZ78 and OZ288 to hamsters infected
Amino ozonides exhibit in vitro activity against <em>Echinococcus multilocularis</em> metacestodes (Publications)
the parasite tissue were equally affected. Complete destruction of the germinal layer was noted at 5 days post exposure. Synthetic ozonides could represent interesting leads that will be further investigated
Community knowledge, perceptions, and practices associated with urogenital schistosomiasis among school-aged children in Zanzibar, United Republic of... (Publications)
we conducted 35 children's discussion groups, 41 in-depth interviews with parents and teachers, and 5 focus group discussions with community members in Zanzibar. Using a modified-grounded theory approach
Detection and characterization of drug-resistant conferring genes in <em>Mycobacterium tuberculosis</em> complex strains: a prospective study in two... (Publications)
associated genetic elements of drug resistant strains were analyzed for mutations. A total of 111 (7.5%), 10 (0.7%) and 40 (2.6%) were mono-resistant to INH, RIF, and MDR, respectively. We found the Ghana
Catalyzing the scale-up of community-based primary healthcare in a rural impoverished region of northern Ghana (Publications)
successfully accelerated CHPS implementation, producing 100% of its targeted community coverage within 5 years of implementation. Coverage in comparison districts also improved. However, the rate of coverage
Parental attitudes towards measles vaccination in the canton of Aargau, Switzerland: a latent class analysis (Publications)
asked to state their agreement in response to 14 belief statements regarding measles vaccination on a 5-point Likert scale. To identify groups of parents showing distinct patterns of attitudes and beliefs
Turkish freshwater and marine macrophyte extracts show in vitro antiprotozoal activity and inhibit FabI, a key enzyme of <em>Plasmodium... (Publications)
l potential. The best antileishmanial activity was exerted by U. lactuca and P. oceanica (IC(50)'s 5.9 and 8.0mug/ml, respectively). Five extracts that demonstrated inhibitory activity towards P. falciparum
Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study (Publications)
confirmed tuberculosis cases than smear microscopy but with equal rapidity. Four additional cases (8.5%) with clinical tuberculosis but negative culture were diagnosed by Xpert. Testing second and third
Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis (Publications)
with mothers without contact (adjusted odds ratio, 0.43; 95% CI, 0.19-0.97). Elevated expression of TLR5 and TLR9 in cord blood was associated with decreased doctor diagnosis of atopic dermatitis. A significant
Clinical and socio-demographic predictors for virologic failure in rural Southern Africa: preliminary findings from CART-1 (Publications)
ratios (aOR). RESULTS: Data from 1,488 patients were analyzed. Overall VF-prevalence was 6.9% (95% CI 5.7-8.3). In univariate analysis, the following were associated with VF: age /=2 hours, disclosure of