Turkish freshwater and marine macrophyte extracts show in vitro antiprotozoal activity and inhibit FabI, a key enzyme of <em>Plasmodium... (Publications)
l potential. The best antileishmanial activity was exerted by U. lactuca and P. oceanica (IC(50)'s 5.9 and 8.0mug/ml, respectively). Five extracts that demonstrated inhibitory activity towards P. falciparum
Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study (Publications)
confirmed tuberculosis cases than smear microscopy but with equal rapidity. Four additional cases (8.5%) with clinical tuberculosis but negative culture were diagnosed by Xpert. Testing second and third
Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis (Publications)
with mothers without contact (adjusted odds ratio, 0.43; 95% CI, 0.19-0.97). Elevated expression of TLR5 and TLR9 in cord blood was associated with decreased doctor diagnosis of atopic dermatitis. A significant
Clinical and socio-demographic predictors for virologic failure in rural Southern Africa: preliminary findings from CART-1 (Publications)
ratios (aOR). RESULTS: Data from 1,488 patients were analyzed. Overall VF-prevalence was 6.9% (95% CI 5.7-8.3). In univariate analysis, the following were associated with VF: age /=2 hours, disclosure of
Population pharmacokinetics and clinical response for artemether-lumefantrine in pregnant and nonpregnant women with uncomplicated <em>Plasmodium... (Publications)
nonpregnant patients. The overall PCR-uncorrected treatment failure rates were 18% in pregnant women and 5% in nonpregnant women (odds ratio [OR] = 4.04; P value of 0.22). A high median day 7 lumefantrine c
Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa (Publications)
average of 4.9 years for 50% of seroconverters to be linked to care (95% confidence intervals (CI): 4.2-5.7). Among all cohort members that were linked to care, the median CD4 count at linkage was 350 cells/muL
Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda (Publications)
infection was associated with anaemia (mean haemoglobin difference of -1.2 g/dL; 95% CI, -0.8 to -1.5 g/dL), fever, underweight, clinically assessed malnutrition and histories of fever, tiredness, weakness
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function (Publications)
novel loci not previously associated with pulmonary function. SNPs in or near DNER (smallest P(JMA = )5.00×10(-11)), HLA-DQB1 and HLA-DQA2 (smallest P(JMA = )4.35×10(-9)), and KCNJ2 and SOX9 (smallest P(JMA
Validation of questions on asthma and wheeze in farming and anthroposophic children (Publications)
questionnaire responses on asthma and wheeze against bronchial response to hypertonic saline (HS) (4.5%) in populations previously shown to have a lower prevalence of asthma and allergies: farmers' children
Inhaled glucocorticoids during pregnancy and offspring pediatric diseases: a national cohort study (Publications)
glucocorticoids for asthma treatment during pregnancy (n=1231; 79.9% budesonide, 17.6% fluticasone, 5.4% beclomethasone, and 0.9% other/unspecified glucocorticoids) and offspring diseases (ICD-10 diagnoses)
