Malaria mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
000 across the sites, with generally low rates in Asia (one site recording no malaria deaths over 0.5 million person-years) and some of the highest rates in West Africa (Nouna, Burkina Faso: 2.47 per 1
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion (Publications)
derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50?0.5 µM), and was posited to exploit the physiological difference between static viral membranes and biogenic
Baby-friendly hospital designation has a sustained impact on continued breastfeeding (Publications)
95% confidence interval [12.0, 17.4]) and any breastfeeding (32.7 weeks, 95% confidence interval [30.5, 39.2]) were the longest for babies born in currently accredited BFHs. Exclusive breastfeeding was
The recurrent campylobacteriosis epidemic over Christmas and New Year in European countries, 2006-2014 (Publications)
of a multiple of the observed notification rates in the weeks before or after the peak e.g. up to 6.5 notifications per 100,000 population per week in Luxembourg. Disease onset of cases notified during
Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study (Publications)
from 11 Swiss cantons. Seroprevalence was 3.7% (95% CI 2.1-4.9) in period 1, 16.2% (95% CI 14.4-17.5) in period 2, and 72.0% (95% CI 70.3-73.8) in period 3, with regional variations. In period 1, younger
Pharmacokinetics of ascending doses of praziquantel in adults infected with <em>Opisthorchis felineus</em> in Western Siberia, Russian Federation (Publications)
-praziquantel, respectively, when patients were given a single 60-mg/kg dose, and they peaked at 1.5 and 2 h for the enantiomers and at 3 h for the metabolite. The herein-generated PK data, together with
Should we treat <em>Blastocystis </em>sp.? A double-blind placebo-controlled randomized pilot trial (Publications)
was positive for other protozoa in 25% (10/40) of the patients. We identified Dientamoeba fragilis in 5, Entamoeba dispar in 3 and Cyclospora cayetanensis in 2 patients. Stratified analysis according to
Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased... (Publications)
measured before and two weeks after administration of a PfSPZ-based malaria vaccine (PfSPZ Vaccine) to 5-month to 61-year-olds in 11 clinical trials in Germany, the US and five countries in Africa, to determine
Comparison of real-time PCR and the Kato-Katz method for the diagnosis of soil-transmitted helminthiasis and assessment of cure in a randomized... (Publications)
y of PCR compared with KK at this time point was 89.1% for T. trichiura, 72.7% for hookworm and 87.5% for A. lumbricoides. Cure rates (CRs) for T. trichiura and A. lumbricoides were slightly lower with
Decreasing incidence of conjunctival squamous cell carcinoma in people with HIV in South Africa (Publications)
for different risk factors using Royston-Parmar flexible parametric survival models. FINDINGS: Among 5,247,968 PWH, 1,059 incident SCCC were diagnosed for a crude overall SCCC incidence rate of 6.8/100,000
