Characterization of the population pharmacokinetics of moxidectin in adults infected with <em>Strongyloides stercoralis</em>: support for a fixed-dose... (Publications)
body weight. High clearance was found in the infected adults (4.47 L/h [95% confidence interval 3.63-5.39] for a 70 kg individual) compared with that previously reported for healthy adults. Model-based
Evaluating different storage media for identification of <em>Taenia saginata</em> proglottids using MALDI-TOF mass spectrometry (Publications)
identified 97.2–99.7% of samples stored in water, sodium chloride, and ethanol, with log-score values ≥2.5, thus indicating reliable species identification. In contrast, no protein spectra were obtained for
Sustainability of a school-based health intervention for prevention of non-communicable diseases in marginalised communities: protocol for a... (Publications)
identified as having an increased risk for non-communicable diseases. Data collection will take place 1.5 and 2 years postintervention and includes quantitative and qualitative methods, such as anthropometric
Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris... (Publications)
lumbricoides and hookworm). Potential effects of the treatment regimens on follow-up prevalences of STH at 5-6 weeks and 3 months post-treatment and pharmacokinetic/ pharmacodynamic parameters will also be assessed
Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
importation of drug resistant parasites into PNG. Although sample size in this location was small (n = 5), our identification of a C580Y mutant in this second location is concerning, highlighting the urgent
Evaluating malaria prevalence and land cover across varying transmission intensity in Tanzania using a cross-sectional survey of school-aged children (Publications)
in cropland cover was associated with an increase in malaria prevalence odds of 2.44 (95% UI: 1.27, 5.11). However, at moderate and higher levels of transmission intensity, no association between cropland
Diarrhoeagenic <em>E. coli </em>occurrence and antimicrobial resistance of extended spectrum beta-lactamases isolated from diarrhoea patients... (Publications)
occurrence of 20.4% (20/98), predominantly among E. coli showed 13.2% (10/76), Klebsiella pneumoniae,35.7%(5/14) and Proteus mirabilis, 57.1%(4/7). Among the ESBL genes detected, blaTEM (n = 14) was common, followed
Cystic fibrosis related diabetes is not associated with maximal aerobic exercise capacity in cystic fibrosis: a cross-sectional analysis of an... (Publications)
covariates were significant predictors of VO2peak (mL.min(-1)), however CFRD [coefficient 82.1, 95% CI -69.5 to 233.8, p = 0.28] was not. CONCLUSIONS: This study suggests no meaningful differences in VO2peak between
Brief research report: quantitative analysis of potential coronary microvascular disease in suspected long-COVID syndrome (Publications)
healthy controls. Results: The stress myocardial blood flow (MBF) was significantly lower [31.8 +/- 5.1 vs. 37.8 +/- 6.0 (mul/g/beat), P < 0.001] and the T2 relaxation time was significantly higher (46
No excess risk of adverse birth outcomes in populations living near special waste landfill sites in Scotland (Publications)
(0.27 to 2.23) for abdominal wall defects (1.32 (0.42-4.17) for hospital admissions), 1.22 (0.28 to 5.38) for surgical correction of gastroschisis and exomphalos and 1.01 (0.96 to 1.07) and 1.01 (0.90 to