Mapping health service coverage inequalities in Africa: a scoping review protocol (Publications)
Synthesis. We preregistered this protocol with the Open Science Framework on 26 July 2022 (https://osf.io/zd5bt). We will consider any empirical research that assesses inequalities in relation to services for
Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an... (Publications)
horbide a (1) was isolated as an active compound with 56% activity against NTS at 50 mug/mL and 22.5% activity against adult S. mansoni at 100 mug/mL but these activities are significantly less than those
Cell penetration, herbicidal activity, and <em>in-vivo</em>-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived... (Publications)
compare the biological properties with those of octaarginines we synthesized Adp(8)-derivatives (Figure5). Intravenouse injection of H-Adp(8)-NH2 into the tail vein of mice with doses as high as 45mol/kg causes
Fecal colonization with multidrug-resistant <em>E. coli</em> among healthy infants in rural Bangladesh (Publications)
ESBL-gene followed by bla(TEM) (41%, n = 30) and bla(OXA-1) (11%, n = 8). A significant proportion (26.5%, n = 22) of 3GCr E. coli was pathogenic, comprising two types, enteroaggregative (EAEC, n = 19) and
Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss... (Publications)
Swissmedic. RESULTS: The response rates of the investigator survey were 8.3% (19/228) for 2012 and 16.5% (47/285) in 2016. The median preparation cost of an RCT was USD 72,400 (interquartile range [IQR]:
Pharmacokinetics of ascending doses of ivermectin in <em>Trichuris trichiura</em>-infected children aged 2-12 years (Publications)
dose-finding trial in rural Cote d'Ivoire, Trichuris trichiura-infected pre-school-aged children (PSAC, 2-5 years) and school-aged children (SAC, 6-12 years) were assigned to 100 or 200 mug/kg and 200, 400 or
A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate... (Publications)
Glasses and Lawa Model interventions. OV and STH infections levels will be evaluated in individuals aged 5-75 years at baseline and will be repeated at follow-up (12 months after the HELM intervention), using
The next 1000 days: building on early investments for the health and development of young children (Publications)
of life that span from conception to two years of age, the next 1000 days of a child's life from 2-5 years of age offer a window of opportunity to promote nurturing and caring environments, establish healthy
The cost of sleeping sickness vector control in Yasa Bonga, a health district in the Democratic Republic of the Congo (Publications)
estimated annual economic cost for protecting an area of 1,925 km2 was 120,000 USD. This translates to 5.3 USD per target used each year, 11 USD per target deployed in the field, 573 USD per linear km treated
Regioselective synthesis of potential non-quinonoid prodrugs of plasmodione: antiparasitic properties against two hemoglobin-feeding parasites and... (Publications)
4a- and the 8a-Ψ-plasmodione regioisomers 1 and 2 (synthesized in six steps with a total yield of 10.5% and 4.1%, respectively. As the expected prodrug effect can only be revealed if the molecule undergoes