Geographic density of landfill sites and risk of congenital anomalies in England (Publications)
risk of congenital anomalies in relation to an index of geographic density of landfill sites across 5x5 km grid squares in England. METHODS: 2 km zones were constructed in a geographical information system [...] was calculated to represent the geographic density of landfill sites within 2 km of births for each 5x5 km grid square, calculated separately for landfill sites handling special, and non-special or unknown [...] certain congenital anomalies and geographic density of special (hazardous)...
Long-term exposure to particulate matter constituents and the incidence of coronary events in 11 European cohorts (Publications)
analysis. 5,157 incident coronary events were identified within 100,166 persons followed on average for 11.5 years. Long-term residential concentrations of PM < 10 mum (PM10), PM < 2.5 mum (PM2.5), and a [...] increase in PM2.5 K were associated with a 6% (hazard ratio and 95% confidence interval: 1.06 [1.01, 1.12]) and 18% (1.18 [1.06, 1.32]) increase in coronary events. Estimates for PM10 Si and PM2.5 Fe were also
Geographic density of landfill sites and risk of congenital anomalies in England (Publications)
risk of congenital anomalies in relation to an index of geographic density of landfill sites across 5x5 km grid squares in England. METHODS: 2 km zones were constructed in a geographical information system [...] was calculated to represent the geographic density of landfill sites within 2 km of births for each 5x5 km grid square, calculated separately for landfill sites handling special, and non-special or unknown [...] certain congenital anomalies and geographic density of special (hazardous)...
Long-term exposure to particulate matter constituents and the incidence of coronary events in 11 European cohorts (Publications)
analysis. 5,157 incident coronary events were identified within 100,166 persons followed on average for 11.5 years. Long-term residential concentrations of PM < 10 mum (PM10), PM < 2.5 mum (PM2.5), and a [...] increase in PM2.5 K were associated with a 6% (hazard ratio and 95% confidence interval: 1.06 [1.01, 1.12]) and 18% (1.18 [1.06, 1.32]) increase in coronary events. Estimates for PM10 Si and PM2.5 Fe were also
A profile of travelers - an analysis from a large Swiss travel clinic (Publications)
Tourism was the main reason for travel (17,875, 81.5%), followed by visiting friends and relatives (VFRs; 1,715, 7.8%), traveling for business (1,223, 5.6%), and "other reasons" (ie, volunteer work, pilgrimage [...] women (23, 3.9%) were observed. Mental disorders were more prominent in VFRs (93, 5.4%) and in travel for "other reasons" (63, 5.7%). The latter stayed for the longest periods abroad; 272 (24.9%) stayed longer [...] pilgrimage, study abroad, and emigration; 1,112, 5.1%). The main...
Prenatal air pollution exposure and early cardiovascular phenotypes in young adults (Publications)
analysis. Prenatal PM10 and PM2.5 exposures were associated with increased CAS. For example, a 2 SD increase in prenatal PM2.5 was associated with CAS indices, including a 5% increase (beta = 1.05, 95% CI [...] beta, a 5% increase (beta = 1.05, 95% CI 1.01-1.10) in Young's elastic modulus and a 5% decrease (beta = 0.95, 95% CI 0.91-0.99) in distensibility. Mutually adjusted models of pre- and postnatal PM2.5 further
A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge... (Publications)
interval: -2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: -0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (-0.3, 15.8)) [...] facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20-40 households for monthly (or more frequent) [...] 8)) and paediatric malnutrition case finding declined by 10% (-0.6 per...
Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects... (Publications)
matter (PM) with diameter of less than 10 mum (PM10), less than 2.5 mum (PM2.5), and between 2.5 and 10 mum (PMcoarse), soot (PM2.5absorbance), nitrogen oxides, and two traffic indicators. We used Cox [...] ratio [HR] 1.22 [95% CI 1.03-1.45] per 10 mug/m3). For PM2.5 the HR was 1.18 (0.96-1.46) per 5 mug/m3. The same increments of PM10 and PM2.5 were associated with HRs for adenocarcinomas of the lung of
Harbor and intra-city drivers of air pollution: findings from a land use regression model, Durban, South Africa (Publications)
and 20.9 microg/m(3) for NO2, SO2, PM10, and PM2.5, respectively) as compared to summer (10.5, 2.8, 20.5, and 8.5 microg/m(3) for NO2, SO2, PM10, and PM2.5, respectively). Furthermore, higher levels of NO2 [...] for Air Pollution Effects (ESCAPE) methodology, concentrations of particulate matter (PM10 and PM2.5), sulphur dioxide (SO2), and nitrogen dioxide (NO2) were measured over a 1-year period, at 41 sites [...] variables being important predictors. The R(2) for PM10 models ranged from 52% to...
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function (Publications)
bovine corneal endothelial cells. Exposure of islets to saturated fatty acid (0.5 mmol/l palmitic acid) in medium containing 5.5, 11.1, or 33.3 mmol/l glucose for 4 days resulted in a five- to ninefold increase [...] fragmentation. In contrast, monounsaturated palmitoleic acid alone (0.5 mmol/l) or in combination with palmitic acid (0.25 or 0.5 mmol/l each) did not affect DNA fragmentation. Increasing concentrations [...] reduced by palmitic acid. Palmitoleic acid enhanced the proliferation...