Serological study of <em>Leptospira interrogans</em> serovar Copenhageni and <em>L. borgpetersenii</em> serovars Tarassovi and Ballum in beef cattle,... (Publications)
and 18.0 (95% CI=15.7-20.5)% for beef cattle, 10.5 (95% CI=9.0-12.1)%, 16.7 (95% CI=14.9-18.6)% and 14.0 (95% CI=12.4-15.8)% for sheep and 6.6 (95% CI=5.3-8.2)%, 15.5 (95% CI=13.5-17.7)% and 3.6 (95% CI=2 [...] 95.1, 73.2 and 56.1% for sheep, 68.5, 48.2 and 29.6% for beef cattle and 73.8, 57.4 and 41.0% for deer, and for Tarassovi, 80.5, 59.7 and 45.1% for sheep, 83.3, 68.5 and 61.1% for beef cattle, and 42.6 [...] animal species and all five Leptospira serovars was 100% at definition > /=1...
In vitro susceptibility of <em>P. falciparum</em> populations from Colombia and Tanzania to a new synthetic peroxide (OZ277) (Publications)
values of 2.5 ng/mL [0.34-8] (4.4 nM [0.6-14]) and Tanzania with 1.5 ng/mL [0.22-10] (2.65 nM [0.4-17.7]). The potency of OZ277 was similar to artesunate, showing median IC(50) values of 1.5 ng/mL [0.42-8 [...] 42-8.6] (3.8 nM [1.1-22.3]) and 1.8 ng/mL [0.2-10] (4.7 nM [0.5-26.04]) in Colombia and Tanzania, respectively. These results support the development of this new antimalarial compound
In vitro susceptibility of <em>P. falciparum</em> populations from Colombia and Tanzania to a new synthetic peroxide (OZ277) (Publications)
values of 2.5 ng/mL [0.34-8] (4.4 nM [0.6-14]) and Tanzania with 1.5 ng/mL [0.22-10] (2.65 nM [0.4-17.7]). The potency of OZ277 was similar to artesunate, showing median IC(50) values of 1.5 ng/mL [0.42-8 [...] 42-8.6] (3.8 nM [1.1-22.3]) and 1.8 ng/mL [0.2-10] (4.7 nM [0.5-26.04]) in Colombia and Tanzania, respectively. These results support the development of this new antimalarial compound
The effects and contribution of childhood diseases on the geographical distribution of all-cause under-five mortality in Uganda (Publications)
acute respiratory infections (ARIs) on all-cause under-five mortality (U5M) at national and sub-national levels. We related all-cause U5M with risks of childhood diseases after adjusting for geographical [...] using population attributable fractions. Results: The overall U5M rate was 90 deaths per 1000 live births. Large regional variations in U5M rates were observed, lowest in Kampala at 56 and highest in the [...] interventions, socio-economic, environmental factors and disease...
The effects and contribution of childhood diseases on the geographical distribution of all-cause under-five mortality in Uganda (Publications)
acute respiratory infections (ARIs) on all-cause under-five mortality (U5M) at national and sub-national levels. We related all-cause U5M with risks of childhood diseases after adjusting for geographical [...] using population attributable fractions. Results: The overall U5M rate was 90 deaths per 1000 live births. Large regional variations in U5M rates were observed, lowest in Kampala at 56 and highest in the [...] interventions, socio-economic, environmental factors and disease...
Evaluating implementation of LEAPS, a youth-led early childhood care and education intervention in rural Pakistan: protocol for a stepped wedge... (Publications)
youth, 18-24 years, as Community Youth Leaders (CYLs) to deliver high-quality ECCE for children, 3.5-5.5 years, in rural Sindh, Pakistan. METHODS: We use a stepped wedge cluster-randomized trial to evaluate [...] collected in cross-sectional surveys of 1089 children (11 children/cluster from 99 clusters) aged 4.5-5.5 years at four timepoints (baseline and at the end of each step). Additionally, we will enroll three [...] across multiple SDG targets. TRIAL REGISTRATION: ClinicalTrials.gov...
Evaluating implementation of LEAPS, a youth-led early childhood care and education intervention in rural Pakistan: protocol for a stepped wedge... (Publications)
youth, 18-24 years, as Community Youth Leaders (CYLs) to deliver high-quality ECCE for children, 3.5-5.5 years, in rural Sindh, Pakistan. METHODS: We use a stepped wedge cluster-randomized trial to evaluate [...] collected in cross-sectional surveys of 1089 children (11 children/cluster from 99 clusters) aged 4.5-5.5 years at four timepoints (baseline and at the end of each step). Additionally, we will enroll three [...] across multiple SDG targets. TRIAL REGISTRATION: ClinicalTrials.gov...
Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
total, 814 persons were enrolled (median age 16 years, 51.5% women). The prevalence was 58.5%. Infection rates increased with age (from 20.0 to 85.5%; P
Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
total, 814 persons were enrolled (median age 16 years, 51.5% women). The prevalence was 58.5%. Infection rates increased with age (from 20.0 to 85.5%; P
Health impact and related cost of ambient air pollution in Tehran (Publications)
economic impact associated with these health effects. Using PM2.5 data from ground-level air pollution measurements in Tehran, we estimated PM2.5 exposure for 349 neighborhoods in Tehran, by the Environmental [...] tal Benefits Mapping and Analysis Program (BenMAP-CE). We considered five scenarios related to PM2.5 levels: an increase to 35mug/m(3); a reduction to 25mug/m(3); a reduction to 15mug/m(3); a reduction [...] guideline value); and a full roll-back, assuming a reduction to 2.4mug/m(3)....