The effect of case management and vector-control interventions on space-time patterns of malaria incidence in Uganda (Publications)
children < 5 years and individuals > /= 5 years, respectively. The ITN effect was not statistically important in older individuals. The space-time patterns of malaria incidence in children < 5 are similar [...] district-aggregated monthly malaria cases, reported by two age groups, defined by a cut-off age of 5 years. The effects of interventions were adjusted for socio-economic and climatic factors. Spatial and [...] pattern with two peaks during May-July and September-December. Average monthly...
Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE) (Publications)
95% CI: 0.88, 1.23 per 10 mug/m3), PM2.5 (adjusted OR = 1.04; 95% CI: 0.88, 1.23 per 5 mug/m3), PM2.5absorbance (adjusted OR = 1.06; 95% CI: 0.95, 1.19 per 10-5/m), traffic load (adjusted OR = 1.10; 95% [...] 10; 95% CI: 0.93, 1.30 per 5,000 vehicles/day on the nearest road). A nonsignificant negative association was estimated for PMcoarse (adjusted OR = 0.98; 95% CI: 0.87, 1.14 per 5 mug/m3). CONCLUSIONS: Results
Sero-prevalence of brucellosis, Q-fever and Rift Valley fever in humans and livestock in Somali Region, Ethiopia (Publications)
individual seropositivity of Q-fever in livestock was 9.6% (95% CI 5.9-15.1) in cattle, 55.7% (95% CI 46.0-65.0) in camels, 48.8% (95% CI 42.5-55.0) in goats, and 28.9% (95% CI 25.0-33.2) in sheep. In humans [...] brucellosis by iELISA. The individual seroprevalence of brucellosis was 2.8(0.9-6.4) in humans, 1.5% (95% CI 0.2-5.2) in cattle and 0.6% (95% CI 0.0-3.2) in camels. This study showed the importance of zoonoses [...] 0% (95% CI 20.4-34.0), with prevalence in males of 28.9% vs 24.2% in...
Long-term exposure to fine particle elemental components and mortality in Europe: results from six European administrative cohorts within the ELAPSE... (Publications)
PM2.5 or NO2 adjustment [pooled HRs (95% CI) per 50ng/m(3) in K: 1.025 (1.008, 1.044), 1.020 (0.999, 1.042) and per 100ng/m(3) in Si: 1.121 (1.039, 1.209), 1.068 (1.022, 1.117) adjusted for PM2.5 and NO2 [...] nickel (Ni), sulfur (S), silicon (Si), vanadium (V) and zinc (Zn) in fine particulate matter (PM2.5) were estimated using 100x100m Europe-wide hybrid land use regression models assigned to the participants' [...] covariates to evaluate associations with natural mortality. Two pollutant...
Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study (Publications)
patients, 245 (72.5%) and 93 (27.5%) had their surgeries at the tertiary and secondary hospitals, respectively. Many were males 192 (56.8%), less than 35 years 164 (48.5%), and 39 (11.5%) developed an SSI [...] Enterococci. The most common isolates were Escherichia coli (12, 24.5%), Klebsiella pneumoniae (10, 20.4%), Acinetobacter baumannii (5, 10.2%), Klebsiella oxytoca (4, 8.2%) and Enterococcus faecalis (4
Safety, immunogenicity and efficacy of PfSPZ vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase... (Publications)
n malaria setting in western Kenya ( NCT02687373 ). Groups of 84 infants each received 4.5 x 10(5), 9.0 x 10(5) or 1.8 x 10(6) PfSPZ Vaccine or saline three times at 8-week intervals. The vaccine was well [...] protection against P. falciparum infection in any dose group at 6 months (VE in the 9.0 x 10(5) dose group = -6.5%, P = 0.598, the primary statistical end point of the study). VE against clinical malaria [...] . We conducted a multi-arm, randomized, double-blind, placebo-controlled trial...
Associations of air pollution and greenness with the nasal microbiota of healthy infants: a longitudinal study (Publications)
(SD) PM2.5 level was 17.1 (3.8mug/m(3)) and mean (SD) NO2 level was 19.7 (7.9mug/m(3)). Increased PM2.5 and increased NO2 were associated with reduced within-subject Ruzicka dissimilarity (PM2.5: per 1mug/m(3) [...] long-term respiratory health. We aimed to examine associations between fine particulate matter (PM2.5), nitrogen dioxide (NO2) and greenness with the nasal microbiota of healthy infants during the first [...] d the association of satellite-based greenness and an 8-day-average...
Preventing dehydration in children with cystic fibrosis who exercise in the heat (Publications)
kg(-1) (P < 0.0005), serum sodium from 143.1 +/- 0.5 to 141.1 +/- 0.7 mmol x L(-1) (P = 0.01) and serum chloride from 109.1 +/- 0.5 to 107.5 +/- 0.5 mmol X L(-1) (P < 0.001). In contrast, the 50 mmol x [...] NaCl concentration higher than 18 mmol x L(-1). METHODS: Eleven subjects with CF (6 girls, 5 boys, ages 10.9-19.5 yr) attended three 3-h sessions of intermittent exercise of moderate intensity (four 20-min
Preventing dehydration in children with cystic fibrosis who exercise in the heat (Publications)
kg(-1) (P < 0.0005), serum sodium from 143.1 +/- 0.5 to 141.1 +/- 0.7 mmol x L(-1) (P = 0.01) and serum chloride from 109.1 +/- 0.5 to 107.5 +/- 0.5 mmol X L(-1) (P < 0.001). In contrast, the 50 mmol x [...] NaCl concentration higher than 18 mmol x L(-1). METHODS: Eleven subjects with CF (6 girls, 5 boys, ages 10.9-19.5 yr) attended three 3-h sessions of intermittent exercise of moderate intensity (four 20-min
The effect of case management and vector-control interventions on space-time patterns of malaria incidence in Uganda (Publications)
children < 5 years and individuals > /= 5 years, respectively. The ITN effect was not statistically important in older individuals. The space-time patterns of malaria incidence in children < 5 are similar [...] district-aggregated monthly malaria cases, reported by two age groups, defined by a cut-off age of 5 years. The effects of interventions were adjusted for socio-economic and climatic factors. Spatial and [...] pattern with two peaks during May-July and September-December. Average monthly...