Modelling to inform prophylaxis regimens to prevent human rabies (Publications)
BACKGROUND: The Strategic Advisory Group of Experts (SAGE) Working Group on rabies vaccines and immunoglobulins was established in 2016 to develop practical and feasible recommendations for prevention
Drug discovery for kinetoplastid diseases: future directions (Publications)
Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) an
HIV infection functionally impairs <em>Mycobacterium tuberculosis</em>-specific CD4 and CD8 T-cell responses (Publications)
HIV infection is the major risk factor predisposing for Mycobacterium tuberculosis (Mtb) progression from latent tuberculosis infection (LTBI) to tuberculosis disease (TB). Since long-term treated avi
SAR of a new antischistosomal urea carboxylic acid (Publications)
Urea carboxylic acids, products of aryl hydantoin hydrolysis, were recently identified as a new antischistosomal chemotype. We now describe a baseline structure-activity relationship (SAR) for this co