Dispersal of <em>Mycobacterium tuberculosis </em>driven by historical European trade in the South Pacific (Publications)
Mycobacterium tuberculosis (Mtb) is a globally distributed bacterial pathogen whose population structure has largely been shaped by the activities of its obligate human host. Oceania was the last majo
Structure, biosynthesis, and bioactivity of photoditritide from <em>Photorhabdus temperata</em> Meg1 (Publications)
A new cyclic peptide photoditritide (1), containing two rare amino acid d-homoarginine residues, was isolated from Photorhabdus temperata Meg1 after the nonribosomal peptide synthetase encoding gene p
Socio-economic inequality and inequity in use of health care services in Kenya: evidence from the fourth Kenya household health expenditure and... (Publications)
BACKGROUND: Kenya is experiencing persistently high levels of inequity in health and access to care services. In 2018, decades of sustained policy efforts to promote equitable, affordable and quality
One hundred years of Suramin (Publications)
Suramin is a hundred years old and still being used to treat the first stage of acute human sleeping sickness, caused by Trypanosoma brucei rhodesiense Suramin is a multifunctional molecule with a wid
Antibiotic exposure among children younger than 5 years in low-income and middle-income countries: a cross-sectional study of nationally... (Publications)
BACKGROUND: Antibiotic resistance is a major threat to global health. Although detailed information about antibiotic use in high-income countries is available, little is known regarding the use of ant
Impact of changes in detection effort on control of visceral leishmaniasis in the Indian subcontinent (Publications)
BACKGROUND: Control of visceral leishmaniasis (VL) on the Indian subcontinent relies on prompt detection and treatment of symptomatic cases. Detection efforts influence the observed VL incidence and h
Strengthening surveillance systems for malaria elimination by integrating molecular and genomic data (Publications)
Unprecedented efforts in malaria control over the last 15 years have led to a substantial decrease in both morbidity and mortality in most endemic settings. However, these progresses have stalled over
Antiprotozoal activity of Turkish <em>Origanum onites</em> essential oil and its components (Publications)
Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential
Antimalarial <em>N</em>1,<em>N</em>3-dialkyldioxonaphthoimidazoliums: synthesis, biological activity, and structure-activity relationships (Publications)
Here we report the nanomolar potencies of N (1),N (3)-dialkyldioxonaphthoimidazoliums against asexual forms of sensitive and resistant Plasmodium falciparum. Activity was dependent on the presence of