An assay to probe <em>Plasmodium falciparum</em> growth, transmission stage formation and early gametocyte development (Publications)
Conversion from asexual proliferation to sexual differentiation initiates the production of the gametocyte, which is the malaria parasite stage required for human-to-mosquito transmission. This protoc
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria (Publications)
Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors (Publications)
Antimalarial drugs have thus far been chiefly derived from two sources-natural products and synthetic drug-like compounds. Here we investigate whether antimalarial agents with novel mechanisms of acti
Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite <em>Plasmodium falciparum</em> (Publications)
Previous studies in model eukaryotes have demonstrated that phosphorylation of heterochromatin protein 1 (HP1) is important for dynamically regulating its various functions. However, in the malaria pa
Does the DOSPERT scale predict risk taking behaviour during travel? A study using smartphones (Publications)
Background: Despite the continuing growth of international tourism, very little research has been done on the link between individual risk attitudes and health behaviours during travel. Our study uses
Impact of subtypes and comorbidities on breast cancer relapse and survival in population-based studies (Publications)
OBJECTIVE: To study the impact of subtypes and comorbidities on breast cancer (BC) relapse and survival in the heterogeneous patients of the real world. METHODS: We identified patients diagnosed with
Epidemiological characterization of malaria in rural southern Tanzania following China-Tanzania pilot joint malaria control baseline survey (Publications)
BACKGROUND: Malaria is an important public health problem in Tanzania. The latest national malaria data suggests rebound of the disease in the country. Anopheles arabiensis, a mosquito species renowne
Residential air pollution does not modify the positive association between physical activity and lung function in current smokers in the ECRHS study (Publications)
BACKGROUND: Very few studies have examined whether a long-term beneficial effect of physical activity on lung function can be influenced by living in polluted urban areas. OBJECTIVE: We assessed wheth