Modelling lymphatic filariasis transmission and control: modelling frameworks, lessons learned and future directions (Publications)
Mathematical modelling provides a useful tool for policy making and planning in lymphatic filariasis control programmes, by providing trend forecasts based on sound scientific knowledge and principles
In Tanzania, the many costs of pay-for-performance leave open to debate whether the strategy is cost-effective (Publications)
Pay-for-performance programs in health care are widespread in low- and middle-income countries. However, there are no studies of these programs' costs or cost-effectiveness. We conducted a cost-effect
Clinical value of the cultural formulation interview in Pune, India (Publications)
CONTEXT: Development of the cultural formulation interview (CFI) in DSM-5 required validation for cross-cultural and global use. AIMS: To assess the overall value (OV) of CFI in the domains of feasibi
Opportunistic infections and immune reconstitution inflammatory syndrome in HIV-1-infected adults in the combined antiretroviral therapy era: a... (Publications)
Despite the availability of effective combined antiretroviral treatment, many patients still present with advanced HIV infection, often accompanied by an AIDS-defining disease. A subgroup of patients
Pharmacokinetics-pharmacodynamics analysis of spiroindolone analogs and KAE609 in a murine malaria model (Publications)
Limited information is available on pharmacokinetic and pharmacodynamic (PK-PD) parameters driving the efficacy of antimalarial drugs. Our objective was to determine dose response relationship of a pa
Activities of N,N' -diarylurea MMV665852 analogs against <em>Schistosoma mansoni</em> (Publications)
There is an unmet need to discover and develop novel antischistosomal drugs. As exemplified by MMV665852, N,N'-diarylureas have recently emerged as a promising antischistosomal chemotype. In this stud
Travelers with immune-mediated inflammatory diseases: are they different? (Publications)
BACKGROUND: Patients with immune-mediated inflammatory diseases (IMIDs) increasingly benefit from improved health due to new therapeutic regimens allowing increasing numbers of such patients to travel
Maternal HIV infection, drug use, and growth of uninfected children in their first 3 years (Publications)
OBJECTIVE: To determine the separate effects of maternal HIV infection and drug use during pregnancy on growth of uninfected children in their first 3 years. DESIGN: Retrospective analysis of measurem