Genetic modification and effector functions of natural killer cells in acute myeloid leukemia (Publications)
Acute myeloid leukemia (AML) is characterized by a poor long-term outcome in the majority of patients following conventional treatment with chemotherapy. Even after allogeneic or autologous hematopoie
Metabolic syndrome risk unexpectedly predicted by traditional food consumption: shifting food systems and health among the Awajun of the Peruvian... (Publications)
BACKGROUND: Dietary changes, especially declines in traditional food diversity and increases in the consumption of processed foods, have previously been shown to increase the risk of developing cardio
Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: <em>Trichuris muris</em>,... (Publications)
Nine hundred million people are infected with the soil-transmitted helminths Ascaris lumbricoides (roundworm), hookworm, and Trichuris trichiura (whipworm). However, low single-dose cure rates of the
Pathogens that cause acute febrile illness among children and adolescents in Burkina Faso, Madagascar and Sudan (Publications)
BACKGROUND: The etiology and optimal clinical management of acute febrile illness (AFI) is poorly understood. METHODS: Blood samples taken from study participants with acute fever (> /=37.5 degrees C)
Quality control of long-lasting insecticidal nets: are we neglecting it? (Publications)
Over 2.2 billion long-lasting insecticidal nets (LLINs) for malaria control have been delivered to recipient countries. LLINs are the largest single item in the global malaria control budget. To be el
Dynamics of intestinal multidrug-resistant bacteria colonisation contracted by visitors to a high-endemic setting: a prospective, daily, real-time... (Publications)
Background: Antimicrobial resistance is highly prevalent in low-income and middle-income countries. International travel contributes substantially to the global spread of intestinal multidrug-resistan
Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
BACKGROUND: Strongyloidiasis represents a major public health issue, particularly in resource-limited countries. Preliminary studies suggest that moxidectin might serve as an alternative to the only a
Evaluation of a duplex real-time PCR in human serum for simultaneous detection and differentiation of <em>Schistosoma mansoni</em> and <em>Schistosoma... (Publications)
BACKGROUND: We evaluated a one-tube multiplex real-time PCR targeting DNA of Schistosoma haematobium complex and S. mansoni complex in serum samples obtained at different German diagnostic centers. ME
Gender differences in the provision of intensive care: a Bayesian approach (Publications)
PURPOSE: It is currently unclear whether management and outcomes of critically ill patients differ between men and women. We sought to assess the influence of age, sex and diagnoses on the probability