Searched for *.

1. Electronic clinical decision support algorithms incorporating point-of-care diagnostic tests in low-resource settings: a target product profile (Publications)

   Electronic clinical decision support algorithms incorporating point-of-care diagnostic tests in low-resource settings: a target product profile

   Relevance:

   Health workers in low-resource settings often lack the support and tools to follow evidence-based clinical recommendations for diagnosing, treating and managing sick patients. Digital technologies, by

2. Molecular detection of <em>Rickettsia </em>spp., <em>Borrelia </em>spp., <em>Bartonella </em>spp. and <em>Yersinia pestis</em> in ectoparasites of... (Publications)

   Molecular detection of <em>Rickettsia </em>spp., <em>Borrelia </em>spp., <em>Bartonella </em>spp. and <em>Yersinia pestis</em> in ectoparasites of endemic and domestic animals in southwest Madagascar

   Relevance:

   Little is known about the presence of vector-borne bacteria in southwest Madagascar. Anthropogenic alteration of natural habitats represents an important driver for the emergence of new diseases. Espe

3. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age (Publications)

   Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

   Relevance:

   BACKGROUND: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal develop

4. Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development (Publications)

   Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development

   Relevance:

   Emerging drug resistance and high-attrition rates in early and late stage drug development necessitate accelerated development of antimalarial compounds. However, systematic and meaningful translation

5. International inventory of occupational exposure information: OMEGA-NET (Publications)

   International inventory of occupational exposure information: OMEGA-NET

   Relevance:

6. <em>In vitro </em>drug efficacy testing against <em>Trypanosoma brucei</em> (Publications)

   <em>In vitro </em>drug efficacy testing against <em>Trypanosoma brucei</em>

   Relevance:

   The recent endorsement of fexinidazole by the European Medicines Agency for the treatment of human African trypanosomiasis has demonstrated the high predictive value of cell-based assays for parasite

7. Model-based integration of genomics and metabolomics reveals SNP functionality in <em>Mycobacterium tuberculosis</em> (Publications)

   Model-based integration of genomics and metabolomics reveals SNP functionality in <em>Mycobacterium tuberculosis</em>

   Relevance:

   Human tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) that vary in virulence and transmissibility. While genome-wide association studies have uncovered several mutat

8. Lerisetron analogues with antimalarial properties: synthesis, structure-activity relationship studies, and biological assessment (Publications)

   Lerisetron analogues with antimalarial properties: synthesis, structure-activity relationship studies, and biological assessment

   Relevance:

9. The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development (Publications)

   The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development

   Relevance:

   AIMS: Imbalances of iron metabolism have been linked to the development of atherosclerosis. However, subjects with hereditary haemochromatosis have a lower prevalence of cardiovascular disease. The ai

10. Ultradian modulation of cortical arousals during sleep: effects of age and exposure to nighttime transportation noise (Publications)

    Ultradian modulation of cortical arousals during sleep: effects of age and exposure to nighttime transportation noise

    Relevance:

    STUDY OBJECTIVES: The present study aimed at assessing the temporal non-rapid eye movement (NREM) EEG arousal distribution within and across sleep cycles and its modifications with aging and nighttime