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1. 3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity (Publications)

   3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity

   Relevance:

   African trypanosomes, Trypanosoma brucei rhodesiense (TBR) and Trypanosoma brucei gambiense (TBG), affect hundreds of thousands of lives in tropical regions of the world. The toxicity of the diamidine

2. Growth of the African lungfish, <em>Protopterus amphibius</em> Peter, in aquaculture (Publications)

   Growth of the African lungfish, <em>Protopterus amphibius</em> Peter, in aquaculture

   Relevance:

3. A trial of the synthetic malaria vaccine SPf66 in Tanzania: rationale and design (Publications)

   A trial of the synthetic malaria vaccine SPf66 in Tanzania: rationale and design

   Relevance:

4. Genetic diversity of <em>Mycobacterium tuberculosis</em> in Madang, Papua New Guinea (Publications)

   Genetic diversity of <em>Mycobacterium tuberculosis</em> in Madang, Papua New Guinea

   Relevance:

   SETTING: Madang and surroundings, Papua New Guinea (PNG). OBJECTIVE: To characterise the genetic diversity and drug susceptibility of Mycobacterium tuberculosis isolates collected in Madang and surrou

5. Pharmacophore model for pentamidine analogs active against <em>Plasmodium falciparum</em> (Publications)

   Pharmacophore model for pentamidine analogs active against <em>Plasmodium falciparum</em>

   Relevance:

   Pentamidine and its analogs constitute a class of compounds that are known to be active against Plasmodium falciparum, which causes the most dangerous malarial infection. Malaria is a widespread disea

6. Safety and efficacy of the RTS,S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a... (Publications)

   Safety and efficacy of the RTS,S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

   Relevance:

   BACKGROUND: The RTS,S/AS01(E) candidate malaria vaccine is being developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 month follow-up data have been

7. Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites (Publications)

   Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites

   Relevance:

   Human African trypanosomiasis (HAT), caused by the protozoan parasite Trypanosoma brucei spp., is a major health problem in sub-Saharan Africa. New drugs are urgently required for the disease. Selecti

8. Structure-activity study of pentamidine analogues as antiprotozoal agents (Publications)

   Structure-activity study of pentamidine analogues as antiprotozoal agents

   Relevance:

   Diamidine 1 (pentamidine) and 65 analogues (2-66) have been tested for in vitro antiprotozoal activities against Trypanosoma brucei rhodesiense, Plasmodium falciparum, and Leishmania donovani, and for

9. Physical activity is inversely associated with multimorbidity in elderly men: results from the KORA-Age Augsburg Study (Publications)

   Physical activity is inversely associated with multimorbidity in elderly men: results from the KORA-Age Augsburg Study

   Relevance:

   OBJECTIVE: Physical activity is suggested to play a key role in the prevention of several chronic diseases. However, data on the association between physical activity and multimorbidity are lacking. M

10. Advances in tuberculosis (Publications)

    Advances in tuberculosis

    Relevance: