Mechanochemical formation of racemic praziquantel hemihydrate with improved biopharmaceutical properties (Publications)
Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the p
Survive and thrive in Brazil: the Boa Vista Early Childhood program: study protocol of a stepped-wedge, randomized controlled trial (Publications)
BACKGROUND: A growing body of evidence suggests that early life health and developmental outcomes can be improved through parental support programs. The objective of this project was to test the feasi
Risk reduction of diarrhea and respiratory infections following a community health education program - a facility-based case-control study in rural... (Publications)
BACKGROUND: Diarrheal and acute respiratory infections remain a major cause of death in developing countries especially among children below 5 years of age. About 80% of all hospital attendances in Ke
Individual aircraft noise exposure assessment for a case-crossover study in Switzerland (Publications)
Accurate exposure assessment is essential in environmental epidemiological studies. This is especially true for aircraft noise, which is characterized by a high spatial and temporal variation. We prop
Interaction between host genes and <em>Mycobacterium tuberculosis </em>lineage can affect tuberculosis severity: evidence for coevolution? (Publications)
Genetic studies of both the human host and Mycobacterium tuberculosis (MTB) demonstrate independent association with tuberculosis (TB) risk. However, neither explains a large portion of disease risk o
Low rates of active hepatitis B and C infections among adults and children living with HIV and taking antiretroviral therapy: a multicenter screening... (Publications)
Lesotho presents the second highest adult human immunodeficiency virus (HIV) prevalence globally. Among people living with HIV, data on hepatitis B virus (HBV) or hepatitis C virus (HCV) co-infection
Investigation of antiplasmodial effects of terpenoid compounds isolated from myrrh (Publications)
As part of our ongoing search for antiprotozoal natural products from plants, we examined different resins from the Burseraceae family. The dichloromethane extract obtained from myrrh, the oleo-gum-re