Design of trials for interrupting the transmission of endemic pathogens (Publications)
BACKGROUND: Many interventions against infectious diseases have geographically diffuse effects. This leads to contamination between arms in cluster-randomized trials (CRTs). Pathogen elimination is th
The epidemiology of residual <em>Plasmodium falciparum</em> malaria transmission and infection burden in an African city with high coverage of... (Publications)
BACKGROUND: In the Tanzanian city of Dar es Salaam, high coverage of long-lasting insecticidal nets (LLINs), larvicide application (LA) and mosquito-proofed housing, was complemented with improved acc
Negligible risk of inducing resistance in <em>Mycobacterium tuberculosis</em> with single-dose rifampicin as post-exposure prophylaxis for leprosy (Publications)
Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the risk of developing leprosy among
Distribution and transmission of <em>Mycobacterium tuberculosis</em> complex lineages among children in peri-urban Kampala, Uganda (Publications)
BACKGROUND: To gain insight into the transmission of tuberculosis (TB) in peri-urban Kampala-Uganda, we performed a household contact study using children as a surrogate for recent transmission of Myc
Accuracy of assessment of eligibility for early medical abortion by community health workers in Ethiopia, India and South Africa (Publications)
OBJECTIVE: To assess the accuracy of assessment of eligibility for early medical abortion by community health workers using a simple checklist toolkit. DESIGN: Diagnostic accuracy study. SETTING: Ethi
Biomarkers of host response predict primary end-point radiological pneumonia in Tanzanian children with clinical pneumonia: a prospective cohort study (Publications)
BACKGROUND: Diagnosing pediatric pneumonia is challenging in low-resource settings. The World Health Organization (WHO) has defined primary end-point radiological pneumonia for use in epidemiological
Experience and lessons from health impact assessment for human rights impact assessment (Publications)
As globalisation has opened remote parts of the world to foreign investment, global leaders at the United Nations and beyond have called on multinational companies to foresee and mitigate negative imp