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1. Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)

   Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies

   Relevance:

   INTRODUCTION: Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by

2. <em>Buruli ulcer</em>: history and disease burden (Publications)

   <em>Buruli ulcer</em>: history and disease burden

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3. <em>Buruli ulcer</em> in Africa (Publications)

   <em>Buruli ulcer</em> in Africa

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4. RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials (Publications)

   RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials

   Relevance:

   A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS,S, now enters pilot i

5. Linking human behaviours and malaria vector biting risk in south-eastern Tanzania (Publications)

   Linking human behaviours and malaria vector biting risk in south-eastern Tanzania

   Relevance:

   To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persis

6. Mycolactone: more than just a cytotoxin (Publications)

   Mycolactone: more than just a cytotoxin

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7. Seroprevalence of <em>Leptospira </em>spp. infection in cattle from central and northern Madagascar (Publications)

   Seroprevalence of <em>Leptospira </em>spp. infection in cattle from central and northern Madagascar

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8. The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes (Publications)

   The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

   Relevance:

   The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper (Tfh) cells. Despite the central role of T

9. Communication barriers in maternity care of allophone migrants: experiences of women, healthcare professionals and intercultural interpreters (Publications)

   Communication barriers in maternity care of allophone migrants: experiences of women, healthcare professionals and intercultural interpreters

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   AIM: To describe communication barriers faced by allophone migrant women in maternity care provision from the perspectives of migrant women, healthcare professionals and intercultural interpreters. BA

10. <em>Mycobacterium tuberculosis</em> lineage 1 genetic diversity in Para, Brazil, suggests common ancestry with east-African isolates potentially... (Publications)

    <em>Mycobacterium tuberculosis</em> lineage 1 genetic diversity in Para, Brazil, suggests common ancestry with east-African isolates potentially linked to historical slave trade

    Relevance:

    Lineage 1 (L1) is one of seven Mycobacterium tuberculosis complex (MTBC) lineages. The objective of this study was to improve the complex taxonomy of L1 using phylogenetic SNPs, and to look for the or