A genome-wide association study on medulloblastoma (Publications)
INTRODUCTION: Medulloblastoma is a malignant embryonal tumor of the cerebellum that occurs predominantly in children. To find germline genetic variants associated with medulloblastoma risk, we conduct
Phototemtide A, a cyclic lipopeptide heterologously expressed from<em> Photorhabdus temperata </em>Meg1, shows selective antiprotozoal activity (Publications)
A new cyclic lipopeptide, phototemtide A (1), was isolated from Escherichia coli expressing the biosynthetic gene cluster pttABC from Photorhabdus temperata Meg1. The structure of 1 was elucidated by
Preclinical antimalarial combination study of M5717, a <em>Plasmodium falciparum</em> elongation factor 2 inhibitor, and pyronaridine, a hemozoin... (Publications)
Antimalarial drug resistance in the Plasmodium falciparum parasite poses a constant challenge for drug development. To mitigate this risk, new antimalarial medicines should be developed as fixed-dose
Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries (Publications)
OBJECTIVE: To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. DESIGN: Two stage time series analysis. SETTING: 406 cities in 20 co
Malaria elimination transmission and costing in the Asia-Pacific: developing an investment case (Publications)
Background: The Asia-Pacific region has made significant progress against malaria, reducing cases and deaths by over 50% between 2010 and 2015. These gains have been facilitated in part, by strong pol