Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis (Publications)
BACKGROUND: Scrub typhus (ST, also known as tsutsugamushi disease) is a common febrile vector-borne disease in South Korea and commonly known as autumn- and female-dominant disease. Although understan
From fragmentation to open access: building an open data portal for health data dissemination (Publications)
Open data is defined as data that can be used and redistributed by anyone with minimal or no restrictions. A design science research methodology was applied to the development of an open data portal f
Total synthesis of tosyl-samroiyotmycin A and its biological profiling (Publications)
A total synthesis of the enantiopure syn,syn-tosyl-samroiyotmycin A, a C2-symmetric 20-membered antimalarial macrodiolide with syn,syn-configuration of the 8,24-dihydroxy-9,25-dimethyl units and it's
Medium-ring keto bislactams with antischistosomal activity (Publications)
We discovered medium-ring keto bislactams as a new antischistosomal chemotype. The ketone functional group and isoindolinone substructure were required for high antischistosomal activity. Aryl substit
Rapid increase in the risk of heat-related mortality (Publications)
Heat-related mortality has been identified as one of the key climate extremes posing a risk to human health. Current research focuses largely on how heat mortality increases with mean global temperatu
Malaria rapid tests, febrile illness management, and child mortality across sub-Saharan African countries (Publications)
IMPORTANCE: A prompt malaria diagnosis is crucial for the management of children with febrile illness in sub-Saharan African countries, where malaria remains a leading cause of mortality among childre
<em>In vitro</em> antischistosomal activity of <em>Bridelia ferruginea, Clausena anisata, Khaya senegalensis, </em>and <em>Vernonia amygdalina</em> (Publications)
BACKGROUND: Schistosomiasis is caused by parasitic flatworms and the disease is endemic to most countries in sub-Saharan Africa including Ghana. The current therapeutic agent for managing this disease
Potential impact of climatic factors on malaria in Rwanda between 2012 and 2021: a time-series analysis (Publications)
BACKGROUND: Malaria remains an important public health problem, particularly in sub-Saharan Africa. In Rwanda, where malaria ranks among the leading causes of mortality and morbidity, disease transmis
Studying target-engagement of anti-infectives by solvent-induced protein precipitation and quantitative mass spectrometry (Publications)
Antimicrobial resistance (AMR) poses a serious threat to global health. The rapid emergence of resistance contrasts with the slow pace of antimicrobial development, emphasizing the urgent need for inn