Tuning and predicting biological affinity: aryl nitriles as cysteine protease inhibitors (Publications)
A series of aryl nitrile-based ligands were prepared to investigate the effect of their electrophilicity on the affinity against the cysteine proteases rhodesain and human cathepsin L. Density functio
Urban agriculture and <em>Anopheles</em> habitats in Dar es Salaam, Tanzania (Publications)
A cross-sectional survey of agricultural areas, combined with routinely monitored mosquito larval information, was conducted in urban Dar es Salaam, Tanzania, to investigate how agricultural and geogr
Treatment with human growth hormone in patients with Prader-Labhart-Willi syndrome reduces body fat and increases muscle mass and physical performance (Publications)
Twelve children with documented Prader-Labhart-Willi syndrome were treated with human growth hormone (24 U/m2/week) during 1 year. The children were divided into three groups: group 1: overweight and
An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease (Publications)
RATIONALE: Although cigarette smoking is the most important cause of chronic obstructive pulmonary disease (COPD), a substantial proportion of COPD cases cannot be explained by smoking alone. OBJECTIV
Independent contribution of parental migrant status and educational level to adiposity and eating habits in preschool children (Publications)
BACKGROUND/OBJECTIVE: Little is known about the precise role of parental migrant status (MS) and educational level (EL) on adiposity and various eating habits in young children. Therefore, we assessed
Improved inhibitors of trypanothione reductase by combination of motifs: synthesis, inhibitory potency, binding mode, and antiprotozoal activities (Publications)
Trypanothione reductase (TR) is an essential enzyme in the trypanothione-based redox metabolism of trypanosomatid parasites. This system is absent in humans and, therefore, offers a promising target f
Eating habits of preschool children with high migrant status in Switzerland according to a new food frequency questionnaire (Publications)
Assessment of eating habits in young children from multicultural backgrounds has seldom been conducted. Our objectives were to study the reproducibility and the results of a food frequency questionnai