Risks and benefits of optimised medical and revascularisation therapy in elderly patients with angina--on-treatment analysis of the TIME trial (Publications)
AIM: To assess treatment effects of optimised medical therapy and PCI or CABG surgery on one-year outcome in patients 75 years old with chronic angina. METHODS AND RESULTS: On-treatment analysis of th
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents (Publications)
A series of phenyl-2,2'-bichalcophene diamidines 1a-h were synthesized from the corresponding dinitriles either via a direct reaction with LiN(TMS)(2), followed by deprotection with ethanolic HCl or t
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents (Publications)
A series of analogues of the naturally occurring antibiotic thiolactomycin (TLM) have been synthesised and evaluated for their ability to inhibit the growth of the malaria parasite, Plasmodium falcipa
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase-2 genes on the metabolism of artemisinin-based... (Publications)
The pharmacogenetics of antimalarials is poorly known, although its application might be critical to optimize treatment. This population pharmacokinetic-pharmacogenetic study aimed at assessing the ef
Characterization of invasive and colonizing isolates of <em>Streptococcus agalactiae</em> in East African adults (Publications)
95 colonizing and 74 invasive Streptococcus agalactiae isolates from Kenyan adults were characterized using capsular serotyping and multilocus sequence typing. 22 sequence types clustering into five c
Evaluation of the discriminatory power of variable number tandem repeat (VNTR) typing of <em>Mycobacterium bovis</em> strains (Publications)
The discriminatory power of variable number tandem repeat (VNTR) typing based on 16 known loci (12 MIRUs, 3 ETRs and VNTR 3232) was assessed for Mycobacterium bovis strains collected sequentially at t
Current status of schistosomiasis and soil-transmitted helminthiasis in Beyla and Macenta Prefectures, Forest Guinea (Publications)
A cross-sectional survey was undertaken in children aged 9-14 years in Beyla and Macenta Prefectures, Forest Guinea. Stool samples were examined by Kato-Katz and urine samples were examined by the cen