Ivermectin dosing strategy to achieve equivalent exposure coverage in children and adults (Publications)
Ivermectin is a commonly-used broad-spectrum antiparasitic drug, yet doses that produce consistent exposure coverage across age have not been characterized and no data are available in children
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis (Publications)
Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious e
Novel 1-methyl-1 <em>H</em>-pyrazole-5-carboxamide derivatives with potent anthelmintic activity (Publications)
A phenotypic screen of two different libraries of small molecules against the motility and development of the parasitic nematode Haemonchus contortus led to the identification of two 1-methyl-1 H-pyra
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis (Publications)
Malaria and cryptosporidiosis, caused by apicomplexan parasites, remain major drivers of global child mortality. New drugs for the treatment of malaria and cryptosporidiosis, in particular, are of hig
Detection of dicistroviruses RNA in blood of febrile Tanzanian children (Publications)
Fever is the leading cause of paediatric outpatient consultations in Sub-Saharan Africa. Although most are suspected to be of viral origin, a putative causative pathogen is not identified in over a qu
Pathways and associated costs of care in patients with confirmed and presumptive tuberculosis in Tanzania: a cross-sectional study (Publications)
OBJECTIVE: To assess pathways and associated costs of seeking care from the onset of symptoms to diagnosis in patients with confirmed and presumptive tuberculosis (TB). DESIGN: Cross-sectional study.
Manganese exposure and working memory-related brain activity in smallholder farmworkers in Costa Rica: results from a pilot study (Publications)
Main sources of manganese (Mn) in the general population are diet and drinking water. Mn is also found in ethylene bisdithiocarbamate (EBDC) fungicides used in agriculture or emitted into the air by f
Fecal colonization with multidrug-resistant <em>E. coli</em> among healthy infants in rural Bangladesh (Publications)
Third generation cephalosporins (3GC) are one of the main choices for treatment of infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Due to their overuse, an increasing trend of r
Insights into the genetic diversity of <em>Mycobacterium tuberculosis</em> in Tanzania (Publications)
BACKGROUND: Human tuberculosis (TB) is caused by seven phylogenetic lineages of the Mycobacterium tuberculosis complex (MTBC), Lineage 1-7. Recent advances in rapid genotyping of MTBC based on single
