<em>Fasciola hepatica</em>: surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78 (Publications)
The tegumental alterations in adult Fasciola hepatica induced by the experimental fasciolide OZ78 were investigated utilizing scanning electron microscopy (SEM). Twelve weeks post-infection with F. he
Artemisinins and synthetic trioxolanes in the treatment of helminth infections (Publications)
PURPOSE OF REVIEW: Helminthiases, including schistosomiasis and food-borne trematodiasis, affect millions of people. Just a few drugs are used for the treatment and control of these diseases. We revie
Anaerobic performance in 5- to 7-yr-old children of low birthweight (Publications)
PURPOSE: This study was intended to determine whether anaerobic muscle performance is deficient in 5- to 7-yr-old children of extremely low birthweight (ELBW, 500-999 g) and very low birthweight (VLBW
Clonorchicidal properties of the synthetic trioxolane OZ78 (Publications)
Because the synthetic trioxolane OZ78 is active against the liver fluke Fasciola hepatica, we were motivated to investigate the in vivo and in vitro activity against another liver fluke, namely Clonor
Beijing sublineages of <em>Mycobacterium tuberculosis</em> differ in pathogenicity in the Guinea pig (Publications)
The Beijing family of Mycobacterium tuberculosis strains is part of lineage 2 (also known as the East Asian lineage). In clinical studies, we have observed that isolates from the sublineage RD207 of l
Combination chemotherapy against <em>Clonorchis sinensis</em>: experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in the... (Publications)
Caused by the Chinese liver fluke Clonorchis sinensis, clonorchiasis is of growing public health importance. Treatment and control of the disease relies on a single drug - praziquantel - and little in