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1. Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus <em>Geomyces auratus</em> (Publications)

   Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus <em>Geomyces auratus</em>

   Relevance:

   Georatusin (1), featuring a highly reduced, methylated polyketide moiety fused to a tryptophan by an amide and ester bond forming a 13-membered ring, was produced by the soil fungus Geomyces auratus.

2. Indoor bacteria and asthma in adults: a multicentre case-control study within ECRHS II (Publications)

   Indoor bacteria and asthma in adults: a multicentre case-control study within ECRHS II

   Relevance:

   Both protective and adverse effects of indoor microbial exposure on asthma have been reported, but mostly in children. To date, no study in adults has used non-targeted methods for detection of indoor

3. High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds (Publications)

   High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds

   Relevance:

   Rapidly spreading antibiotic resistance and the low discovery rate of new antimicrobial compounds demand more effective strategies for early drug discovery. One bottleneck in the drug discovery pipeli

4. Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic... (Publications)

   Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against <em>T. brucei </em>and <em>T. congolense</em>

   Relevance:

   African trypanosomiasis is a neglected parasitic disease that is still of great public health relevance, and a severe impediment to agriculture in endemic areas. The pathogens possess certain unique m

5. Ecology and evolution of <em>Mycobacterium tuberculosis</em> (Publications)

   Ecology and evolution of <em>Mycobacterium tuberculosis</em>

   Relevance:

   Tuberculosis (TB) is the number one cause of human death due to an infectious disease. The causative agents of TB are a group of closely related bacteria known as the Mycobacterium tuberculosis comple

6. How elimination of lymphatic filariasis as a public health problem in the Kingdom of Cambodia was achieved (Publications)

   How elimination of lymphatic filariasis as a public health problem in the Kingdom of Cambodia was achieved

   Relevance:

   BACKGROUND: Endemicity of lymphatic filariasis (LF) in Cambodia was proven in 1956 when microfilariae were detected in mosquitos in the Kratie province. In 2001, an extensive study confirmed the prese

7. Insufficient fruit and vegetable intake in a low- and middle-income setting: a population-based survey in semi-urban Tanzania (Publications)

   Insufficient fruit and vegetable intake in a low- and middle-income setting: a population-based survey in semi-urban Tanzania

   Relevance:

   A daily intake of 5 portions of fruit and vegetables (FV) is recommended for protection against non-communicable diseases (NCDs). Inadequate FV intake is a global problem but resource-poor countries l

8. Purine- and pyrimidine-triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus (Publications)

   Purine- and pyrimidine-triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus

   Relevance:

9. DNA methylation in childhood asthma: an epigenome-wide meta-analysis (Publications)

   DNA methylation in childhood asthma: an epigenome-wide meta-analysis

   Relevance:

10. Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites (Publications)

    Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites

    Relevance: