Whole genome sequencing for drug resistance profile prediction in<em> Mycobacterium tuberculosis</em> (Publications)
Whole genome sequencing allows rapid detection of drug-resistant Mycobacterium tuberculosis isolates. However, the availability of high-quality data linking quantitative phenotypic drug susceptibility
Age-related comorbidities and mortality in people living with HIV in rural Tanzania: data from a prospective cohort study (Publications)
OBJECTIVE: Causes of morbidity and mortality of people living with HIV are changing with access to antiretroviral therapy and increased life expectancy. Age-related data on comorbidities and their imp
Indigenous <em>Plasmodium malariae</em> infection in an endemic population at the Thai-Myanmar border (Publications)
Plasmodium malariae is a neglected malaria parasite. It has wide geographic distribution and, although often associated with mild malaria, is linked to a high burden of anemia and nephrotic syndromes.
Pharmacokinetics of albendazole, albendazole sulfoxide and albendazole sulfone determined from plasma, blood, dried blood spots and Mitra® samples of... (Publications)
Albendazole is an effective anthelmintic intensively used for decades. However, profound pharmacokinetic (PK) characterization is missing in children, the population mostly affected by helminth infect
A comprehensive framework for physiologically-based pharmacokinetic modelling in Matlab® (Publications)
Physiologically based pharmacokinetic (PBPK) models are useful tools to predict clinical scenarios for special populations for whom there are high hurdles to conduct clinical trials such as children o