Comparability between insecticide resistance bioassays for mosquito vectors: time to review current methodology? (Publications)
BACKGROUND: Insecticides play an integral role in the control of mosquito-borne diseases. With resistance to insecticides on the rise, surveillance of the target population for optimal choice of insec
Toward measuring <em>Schistosoma</em> response to praziquantel treatment with appropriate descriptors of egg excretion (Publications)
BACKGROUND: The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission
Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions (Publications)
A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone. Since the underlying mechanism
The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and... (Publications)
BACKGROUND: The RTS,S/AS01 malaria vaccine candidate recently completed Phase III trials in 11 African sites. Recommendations for its deployment will partly depend on predictions of public health impa
Recommendations for malaria prevention in moderate to low risk areas: travellers' choice and risk perception (Publications)
BACKGROUND: The considerable malaria decline in several countries challenges the strategy of chemoprophylaxis for travellers visiting moderate- to low-risk areas. An international consensus on the bes
Development of a quantitative methodology to assess the impacts of urban transport interventions and related noise on well-being (Publications)
Well-being impact assessments of urban interventions are a difficult challenge, as there is no agreed methodology and scarce evidence on the relationship between environmental conditions and well-bein
An atypical mitochondrial carrier that mediates drug action in <em>Trypanosoma brucei</em> (Publications)
Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library