Bromopyrrole alkaloids as lead compounds against protozoan parasites (Publications)
In the present study, 13 bromopyrrole alkaloids, including the oroidin analogs hymenidin (2), dispacamide B (3) and dispacamide D (4), stevensine (5) and spongiacidin B (6), their derivatives lacking
Discovery and evaluation of thiazinoquinones as anti-protozoal agents (Publications)
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 muM)
Scenario planning for community development in Vietnam: a new tool for integrated health approaches? (Publications)
BACKGROUND: Like many countries in Southeast Asia, Vietnam's rapid population and economic growth has met challenges in infrastructure development, especially sanitation in rural areas. OBJECTIVE: As
Factors affecting adoption, implementation fidelity, and sustainability of the redesigned community health fund in Tanzania: a mixed methods protocol... (Publications)
BACKGROUND: Despite the implementation of various initiatives to address low enrollment in voluntary micro health insurance (MHI) schemes in sub-Saharan Africa, the problem of low enrollment remains u
A qualitative appraisal of stakeholder reactions to a tool for burden of disease-based health system budgeting in Ghana (Publications)
BACKGROUND: In 2010, the Ghana Health Service launched a program of cooperation with the Tanzania Ministry of Health and Social Welfare that was designed to adapt Tanzania's PLANREP budgeting and repo
Anti-protozoal activities of cembrane-type diterpenes from Vietnamese soft corals (Publications)
Based on our previous finding that certain cembranoid diterpenes possess selective toxicity against protozoan pathogens of tropical diseases such as Trypanosoma and Plasmodium, we have subjected a ser
Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical<em> Trypanosoma</em> <em>brucei... (Publications)
Aquaglyceroporin-2 is a known determinant of melarsoprol-pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2-AQP3 tandem locus was describ