Multistage antiplasmodium activity of astemizole analogues and inhibition of hemozoin formation as a contributor to their mode of action (Publications)
A drug repositioning approach was leveraged to derivatize astemizole (AST), an antihistamine drug whose antimalarial activity was previously identified in a high-throughput screen. The multistage acti
Association of objectively measured and perceived environment with accelerometer-based physical activity and cycling: a Swiss population-based... (Publications)
OBJECTIVES: We tested whether objectively assessed neighbourhood characteristics are associated with moderate-to vigorous physical activity (MVPA) and cycling in Swiss children and adolescents and ass
Measuring mobility, disease connectivity and individual risk: a review of using mobile phone data and mHealth for travel medicine (Publications)
RATIONALE FOR REVIEW: The increasing mobility of populations allows pathogens to move rapidly and far, making endemic or epidemic regions more connected to the rest of the world than at any time in hi
Epidemiological links between malaria parasitaemia and hypertension: findings from a population-based survey in rural Côte d'Ivoire (Publications)
BACKGROUND: Although potential links between malaria parasitaemia and hypertension have been hypothesized, there is paucity of epidemiologic evidence on this link. We investigated in a population-base
Design, synthesis, and biological evaluation of new 1-(Aryl-1<em>H</em>-pyrrolyl)(phenyl)methyl-1<em>H</em>-imidazole derivatives as antiprotozoal... (Publications)
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently. The new analogs possess
Detection and characterization of ESBL-producing<em> Escherichia coli</em> from humans and poultry in Ghana (Publications)
Introduction: The increasing incidence of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in sub-Saharan Africa is of serious concern. Studies from countries wi