Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity (Publications)
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial
Travel medicine and mHealth technology: a study using smartphones to collect health data during travel (Publications)
BACKGROUND: mHealth methodology such as smartphone applications offers new opportunities to capture the full range of health risks during travel in real time. Our study aims to widen the scope of trav
Hemolysis after oral artemisinin combination therapy for uncomplicated <em>Plasmodium falciparum</em> malaria (Publications)
Episodes of delayed hemolysis 2-6 weeks after treatment of severe malaria with intravenous artesunate have been described. We performed a prospective observational study of patients with uncomplicated
The antiprotozoal potencies of newly prepared 3-azabicyclo[3.2.2]nonanes (Publications)
3-Azabicyclo[3.2.2]nonanes are already reported as antiprotozoal agents. Structural variations were performed by attachment of several basic side chains, being part of drugs in use, to the ring nitrog
Community co-designed schistosomiasis control interventions for school-aged children in Zanzibar (Publications)
Top-down biomedical interventions to control schistosomiasis in sub-Saharan Africa have had limited success, primarily because they fail to engage with the social, political, economic and ecological c
Inhibition of <em>Plasmodium falciparum</em> Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles (Publications)
Malaria caused by the protozoan parasite Plasmodium falciparum (Pf) remains a major public health problem throughout the developing world. One molecular target that should receive more attention is th
Pregnant women and infants as sentinel populations to monitor prevalence of malaria: results of pilot study in Lake Zone of Tanzania (Publications)
BACKGROUND: As malaria control interventions are scaled-up, rational approaches are needed for monitoring impact over time. One proposed approach includes monitoring the prevalence of malaria infectio
Biomonitoring human exposure to household air pollution and association with self-reported health symptoms- a stove intervention study in Peru (Publications)
BACKGROUND: Household air pollution (HAP) from indoor biomass stoves contains harmful pollutants, such as polycyclic aromatic hydrocarbons (PAHs), and is a leading risk factor for global disease burde
Within host evolution selects for a dominant genotype of <em>Mycobacterium tuberculosis</em> while T cells increase pathogen genetic diversity (Publications)
Molecular epidemiological assessments, drug treatment optimization, and development of immunological interventions all depend on understanding pathogen adaptation and genetic variation, which differ f
Incidence and types of adverse events during mass vaccination campaign with the meningococcal A conjugate vaccine (MENAFRIVACTM) in Cameroon (Publications)
PURPOSE: A new vaccine against meningitis A was introduced in Africa meningitis belt in 2010. This study was planned to describe the incidence and types of adverse events following immunization (AEFIs
