Genome-wide association study identifies five loci associated with lung function (Publications)
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory
The influence of HIV on the evolution of <em>Mycobacterium tuberculosis</em> (Publications)
HIV significantly affects the immunological environment during tuberculosis co-infection, and therefore may influence the selective landscape upon which M. tuberculosis evolves. To test this hypothesi
Genome-wide interaction analysis of air pollution exposure and childhood asthma with functional follow-up (Publications)
RATIONALE: The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent, and may depend on genetic factors. OBJECTIVES: To identi
Efficacy and safety of praziquantel against light infections of <em>Opisthorchis viverrini</em>: a randomised parallel single blind dose-ranging trial (Publications)
BACKGROUND: The liver fluke Opisthorchis viverrini, highly prevalent in Southeast Asia, is an important public health burden, including a risk factor for developing an aggressive bile duct cancer, cho
Sensitisation to Ambrosia in Switzerland: a public health threat on the wait (Publications)
BACKGROUND: Ambrosia artemisiifolia (short name = Ambrosia common ragweed) pollen is a potent allergen and has recently been found in Switzerland, spreading from the southwest of the country. The aim
Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a... (Publications)
BACKGROUND: Low concentrations of the anti-inflammatory protein CC16 (approved symbol SCGB1A1) in serum have been associated with accelerated decline in forced expiratory volume in 1 s (FEV1) in patie
HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction (Publications)
Reduced exposure to particulate matter with a 50% cut-off aerodynamic diameter of 10 microm (PM(10)) attenuated age-related lung function decline in our cohort, particularly in the small airways. We h