Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas (Publications)
Cruciferous vegetables, especially broccoli, may prevent cancer through anticarcinogenic compounds. For example, broccoli contains isothiocyanates that induce carcinogen-detoxifying enzymes. Glutathio
Comparison of the in vitro drug sensitivity of <em>Trypanosoma brucei gambiense</em> strains from West and Central Africa isolated in the periods... (Publications)
The situation of human African trypanosomiasis remains serious with one of the main threats being the increasing number of relapses or treatment failures after melarsoprol treatment. In order to inves
The U.S. Environmental Protection Agency Particulate Matter Health Effects Research Centers Program: a midcourse report of status, progress, and plans (Publications)
In 1998 Congress mandated expanded U.S. Environmental Protection Agency (U.S. EPA) health effects research on ambient air particulate matter (PM) and a National Research Council (NRC) committee to pro
Harnessing the wealth of Chinese scientific literature: schistosomiasis research and control in China (Publications)
ABSTRACT: The economy of China continues to boom and so have its biomedical research and related publishing activities. Several so-called neglected tropical diseases that are most common in the develo
Occupational exposure to inhalative irritants and methacholine responsiveness (Publications)
OBJECTIVES: Occupational exposures to inhalative irritants have been associated with an increased reporting of respiratory symptoms in previous studies. Methacholine responsiveness represents a contin
Passive smoking exposure in adults and chronic respiratory symptoms (SAPALDIA Study) (Publications)
The association between passive exposure to tobacco smoke and respiratory symptoms was examined in a sample of 4,197 never-smoking adults. They constituted the never-smoking subsample of a random samp
Etude suisse sur la pollution de l'air et les maladies respiratoires chez l'adulte (SAPALDIA) (Publications)
Long-term health effects of moderate ambient air pollution are rarely investigated. In Switzerland, no large-scale study has addressed this issue so far. Important results of the Swiss Study on Air Po
Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of <em>Glossina morsitans</em> (Publications)
EP and GPEET procyclin, the major surface glycoproteins of procyclic forms of Trypanosoma brucei, are truncated by proteases in the midgut of the tsetse fly Glossina morsitans morsitans. We show that
Synthesis of a series of N(6)-substituted adenosines with activity against trypanosomatid parasites (Publications)
The involvement of purine salvage in the accumulation of current trypanocidal drugs is important for the treatment of African sleeping sickness. The substrate specificity of essential nucleoside trans