The complete mitochondrial genome of the rodent intra-arterial nematodes <em>Angiostrongylus cantonensis</em> and <em>Angiostrongylus... (Publications)
The two rodent intra-arterial nematodes, Angiostrongylus cantonensis and Angiostrongylus costaricensis, can cause human ill-health. The present study aimed to characterize and compare the mitochondria
Mortality due to Chagas disease in Brazil from 1979 to 2009: trends and regional differences (Publications)
INTRODUCTION: Studies on mortality due to parasitic diseases such as Chagas disease are useful to understand the epidemiology and to plan and guide control measures for these diseases. We analyzed mor
Pouched rats' detection of tuberculosis in human sputum: comparison to culturing and polymerase chain reaction (Publications)
Setting. Tanzania. Objective. To compare microscopy as conducted in direct observation of treatment, short course centers to pouched rats as detectors of Mycobacterium tuberculosis. Design. Ten pouche
<em>In vitro</em> assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of <em>Plasmodium falciparum</em> (Publications)
OBJECTIVES: Using synchronous cultures of Plasmodium falciparum malaria, the stage sensitivity of the parasite to OZ277 (RBx-11160), the first fully synthetic antimalarial peroxide that has entered Ph
An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from <em>Eupatorium perfoliatum</em> (Publications)
The CH(2)Cl(2) extract of aerial parts of Eupatorium perfoliatum L. exhibits antiprotozoal activity under in vitro conditions, especially against Plasmodium falciparum (IC(50)=2.7mug/ml). The search f
The emergence of angiostrongyliasis in the People's Republic of China: the interplay between invasive snails, climate change and transmission... (Publications)
P> 1. Only few freshwater snail species transmit the rat lungworm Angiostrongylus cantonensis, which is partially explained by the low likelihood of contact between snails and infected rat faeces. The
Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models (Publications)
There are currently only four clinical drugs available for treating human African trypanosomiasis (HAT), three of which were developed over 60years ago. Despite years of effort, there has been relativ