Physical inactivity caused economic burden depends on regional cultural differences (Publications)
Physical inactivity is a major risk factor for numerous non-communicable diseases which dominate the overall burden of disease in Switzerland. We aimed to estimate the burden attributable to adult phy
Investigating sulfoxide-to-sulfone conversion as a prodrug strategy for a phosphatidylinositol 4-kinas inhibitor in a humanized mouse model of malaria (Publications)
The in vivo antimalarial efficacies of two PI4K inhibitors, a 3,5-diaryl-2-aminopyrazine sulfoxide and its corresponding sulfone metabolite, were evaluated in the NOD-scid IL2Rgamma(null) (NSG) murine
Land use regression modelling of outdoor NO2 and PM2.5 concentrations in three low income areas in the Western Cape Province, South Africa (Publications)
Air pollution can cause many adverse health outcomes, including cardiovascular and respiratory disorders. Land use regression (LUR) models are frequently used to describe small-scale spatial variation
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing (Publications)
Kinetoplastid parasites-trypanosomes and leishmanias-infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxabo