A high-performance liquid chromatography and nuclear magnetic resonance spectroscopy-based analysis of commercially available praziquantel tablets (Publications)
The amount of active ingredient in 20 commercially sourced batches of praziquantel (PZQ) tablets was determined using a high-performance liquid chromatography-ultraviolet (HPLC-UV) assay in conjunctio
Perception par les éleveurs des nuisances causées par les insectes et les tiques aux bovins dans le Canton du Jura (Publications)
During summer 2005, a survey of 172 farmers from the Canton Jura was carried out to determine their perception of the nuisances caused by insects and ticks to cattle. The presence of ticks was signifi
Measuring exposure to <em>Schistosoma japonicum</em> in China. III. Activity diaries, snail and human infection, transmission ecology and options for... (Publications)
We used activity diaries and snail detection to relate water contact and Schistosoma japonicum infection among a cohort of 178 residents on two islands in the Dongting Lake, China. Water exposure to e
Five-year impact of repeated praziquantel treatment on subclinical morbidity due to<em> Schistosoma japonicum</em> in China (Publications)
We report the 5-year impact (1996-2001) of repeated praziquantel chemotherapy on subclinical morbidity related to Schistosoma japonicum infection. We repeated stool examinations and hepatosplenic ultr
Fabclavines: bioactive peptide-polyketide-polyamino hybrids from <em>Xenorhabdus</em> (Publications)
The structure of the fabclavines-unique mixtures of nonribosomally derived peptide-polyketide hybrids connected to an unusual polyamino moiety-has been solved by detailed NMR and MS methods. These com
Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack (Publications)
Sterols are an essential class of lipids in eukaryotes, where they serve as structural components of membranes and play important roles as signaling molecules. Sterols are also of high pharmacological
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
We investigated the association between exposure to radio-frequency electromagnetic fields (RF-EMFs) from broadcast transmitters and childhood cancer. First, we conducted a time-to-event analysis incl
Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase (Publications)
The causative agents of the parasitic disease human African trypanosomiasis belong to the family of trypanosomatids. These parasitic protozoa exhibit a unique thiol redox metabolism that is based on t