Applications of quantitative microbial risk assessment to respiratory pathogens and implications for uptake in policy: a state-of-the-science review (Publications)
BACKGROUND: Respiratory tract infections are major contributors to the global disease burden. Quantitative microbial risk assessment (QMRA) holds potential as a rapidly deployable framework to underst
Robenidine derivatives as potential antischistosomal drug candidates (Publications)
Schistosomiasis caused by Schistosoma spp. is a disease that causes a considerable health burden to millions of people worldwide. The limited availability of effective drugs on the market and the incr
Prevalence and predictors of residual antibiotics in children's blood in community settings in Tanzania (Publications)
OBJECTIVE: Children account for a significant proportion of antibiotic consumption in low- and middle-income countries, with overuse occurring in formal and informal health sectors. This study assesse
Severe outcomes of malaria in children under time-varying exposure (Publications)
In malaria epidemiology, interpolation frameworks based on available observations are critical for policy decisions and interpreting disease burden. Updating our understanding of the empirical evidenc
Multiplex PCR for bacterial, viral and protozoal pathogens in persistent diarrhoea or persistent abdominal pain in Côte d'Ivoire, Mali and Nepal (Publications)
In contrast to acute diarrhoea, the aetiology of persistent digestive disorders (≥ 14 days) is poorly understood in low-resource settings and conventional diagnostic approaches lack accuracy. In this
Seroprevalence of <em>Rickettsia</em> spp. and <em>Orientia tsutsugamushi</em> in indigenous populations from the Sierra Nevada de Santa Marta,... (Publications)
Background: Rickettsia spp. are vector-borne zoonotic pathogens that cause febrile illness in humans. Rickettsioses is not included in the Colombian national surveillance system and is subsequently ex
Incomplete<em> Plasmodium falciparum</em> growth inhibition following piperaquine treatment translates into increased parasite viability in the <em>in... (Publications)
Antimalarial resistance to the first-line partner drug piperaquine (PPQ) threatens the effectiveness of artemisinin-based combination therapy. In vitro piperaquine resistance is characterized by incom
Norovirus acute gastroenteritis among US and European travellers to areas of moderate to high risk of travellers' diarrhoea: a prospective cohort... (Publications)
BACKGROUND: Acute gastroenteritis (AGE) is a major medical condition for travellers worldwide, particularly travellers to low- and middle-income countries. Norovirus (NoV) is the most common cause of
