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1. Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of... (Publications)

   Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of particulate matter pollution in the Swiss SAPALDIA regions

   Relevance:

   BACKGROUND: Land Use Regression (LUR) is a popular method to explain and predict spatial contrasts in air pollution concentrations, but LUR models for ultrafine particles, such as particle number conc

2. Authors' reply to "Gold stage 1 is crying wolf" by PL Enright (Publications)

   Authors' reply to "Gold stage 1 is crying wolf" by PL Enright

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3. Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction... (Publications)

   Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction analysis

   Relevance:

   Background: Both air pollution and genetic variation have been shown to affect lung function. Their interaction has not been studied on a genome-wide scale to date. Objectives: We aimed to identify, i

4. Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)

   Genome-wide association and functional follow-up reveals new loci for kidney function

   Relevance:

   Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s

5. Reduced exposure to PM10 and attenuated age-related decline in lung function (Publications)

   Reduced exposure to PM10 and attenuated age-related decline in lung function

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   BACKGROUND: Air pollution has been associated with impaired health, including reduced lung function in adults. Moving to cleaner areas has been shown to attenuate adverse effects of air pollution on l

6. Early menarche and new onset of asthma: results from the SAPALDIA cohort study (Publications)

   Early menarche and new onset of asthma: results from the SAPALDIA cohort study

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7. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)

   1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

   Relevance:

   HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re

8. Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project (Publications)

   Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project

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9. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies (Publications)

   Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

   Relevance:

   BACKGROUND: Epigenetic variations in peripheral blood have potential as biomarkers for disease. This systematic review assesses the association of lung function and chronic obstructive pulmonary disea

10. Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)

    Infectious diseases are associated with carotid intima media thickness in adolescence

    Relevance:

    OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious