Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane... (Publications)
Various natural products with the chromane and chromene scaffold exhibit high antiprotozoal activity. The natural product encecalin (7) served as key intermediate for the synthesis of different ethers
Improved characterization of visual evoked potentials in multiple sclerosis by topographic analysis (Publications)
In multiple sclerosis (MS), the combination of visual, somatosensory and motor evoked potentials (EP) has been shown to be highly correlated with the Expanded Disability Severity Scale (EDSS) and to p
Mathematical models of contact patterns between age groups for predicting the spread of infectious diseases (Publications)
The spread of an infectious disease is sensitive to the contact patterns in the population and to precautions people take to reduce the transmission of the disease. We investigate the impact that diff
More than one way to produce protein diversity: duplication and limited alternative splicing of an adhesion molecule gene in basal arthropods (Publications)
Exon duplication and alternative splicing evolved multiple times in metazoa and are of overall importance in shaping genomes and allowing organisms to produce many fold more proteins than there are ge
Cutaneous leishmaniasis in Switzerland: first experience with species-specific treatment (Publications)
BACKGROUND: Different species of the genus Leishmania can cause cutaneous (CL) and mucosal leishmaniasis (ML). PCR-based tests allow a rapid diagnosis and determination of the species, thereby enablin
Use of lower gastrointestinal endoscopy and fecal occult blood test in the 2007 Swiss health interview survey respondents aged 50 years and older (Publications)
Background and study aims: Colorectal cancer (CRC) incidence ranks third among all cancers in Switzerland. Screening the general population could decrease CRC incidence and mortality. The aim of this