Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy (Publications)
The antiplasmodial activity, DMPK properties, and efficacy of a series of quinoline-4-carboxamides are described. This series was identified from a phenotypic screen against the blood stage of Plasmod
Validation of a rapid rabies diagnostic tool for field surveillance in developing countries (Publications)
BACKGROUND: One root cause of the neglect of rabies is the lack of adequate diagnostic tests in the context of low income countries. A rapid, performance friendly and low cost method to detect rabies
Ebola virus disease, Democratic Republic of the Congo, 2014 (Publications)
During July-November 2014, the Democratic Republic of the Congo underwent its seventh Ebola virus disease (EVD) outbreak. The etiologic agent was Zaire Ebola virus; 66 cases were reported (overall cas
Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a... (Publications)
BACKGROUND: Depression and alcohol use disorder have been shown to be associated with poor adherence to antiretroviral therapy (ART). Studies examining their association with viral suppression in rura
Enhancing collaboration between China and African countries for schistosomiasis control (Publications)
Schistosomiasis remains an important public health issue, with a large number of cases reported across sub-Saharan Africa, and parts of Asia and Latin America. China was once highly endemic, but has m
Unique human immune signature of Ebola virus disease in Guinea [Letter] (Publications)
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very little is known abo
The potential of food fortification to add micronutrients in young children and women of reproductive age - findings from a cross-sectional survey in... (Publications)
Poor micronutrient intakes are a major contributing factor to the high burden of micronutrient deficiencies in Cote d'Ivoire. Large-scale food fortification is considered a cost-effective approach to
The central role of national programme management for the achievement of malaria elimination: a cross case-study analysis of nine malaria programmes (Publications)
BACKGROUND: A malaria eradication goal has been proposed, at the same time as a new global strategy and implementation framework. Countries are considering the strategies and tools that will enable pr