Single ascending dose pharmacokinetic study of tribendimidine in <em>Opisthorchis viverrini</em>-infected patients (Publications)
OBJECTIVES: Praziquantel is the only drug available for treatment of Opisthorchis viverrini infections. Tribendimidine has emerged as potential treatment alternative, however its pharmacokinetic (PK)
Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity (Publications)
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial
Community co-designed schistosomiasis control interventions for school-aged children in Zanzibar (Publications)
Top-down biomedical interventions to control schistosomiasis in sub-Saharan Africa have had limited success, primarily because they fail to engage with the social, political, economic and ecological c
Should viral load thresholds be lowered? Revisiting the WHO definition for virologic failure in patients on antiretroviral therapy in resource-limited... (Publications)
The World Health Organization (WHO) guidelines on antiretroviral therapy (ART) define treatment failure as 2 consecutive viral loads (VLs) > /=1000 copies/mL. There is, however, little evidence suppor
The antiprotozoal potencies of newly prepared 3-azabicyclo[3.2.2]nonanes (Publications)
3-Azabicyclo[3.2.2]nonanes are already reported as antiprotozoal agents. Structural variations were performed by attachment of several basic side chains, being part of drugs in use, to the ring nitrog
Hemolysis after oral artemisinin combination therapy for uncomplicated <em>Plasmodium falciparum</em> malaria (Publications)
Episodes of delayed hemolysis 2-6 weeks after treatment of severe malaria with intravenous artesunate have been described. We performed a prospective observational study of patients with uncomplicated
Travel medicine and mHealth technology: a study using smartphones to collect health data during travel (Publications)
BACKGROUND: mHealth methodology such as smartphone applications offers new opportunities to capture the full range of health risks during travel in real time. Our study aims to widen the scope of trav
Correcting India's chronic shortage of drug inspectors to ensure the production and distribution of safe, high-quality medicines (Publications)
BACKGROUND: Good drug regulation requires an effective system for monitoring and inspection of manufacturing and sales units. In India, despite widespread agreement on this principle, ongoing shortage
