Host-directed therapies for infectious diseases: current status, recent progress, and future prospects (Publications)
Despite extensive global efforts in the fight against killer infectious diseases, they still cause one in four deaths worldwide and are important causes of long-term functional disability arising from
Population pharmacokinetic modeling of tribendimidine metabolites in <em>Opisthorchis viverrini</em>-infected adults (Publications)
There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unkno
Efficacy and safety of oxantel pamoate in school-aged children infected with <em>Trichuris trichiura</em> on Pemba island, Tanzania: a parallel,... (Publications)
BACKGROUND: Commonly used drugs for preventive chemotherapy against soil-transmitted helminths (ie, albendazole and mebendazole) show low efficacy against Trichuris trichiura. Recent studies with oxan
Cross-reactivity pattern of Asian and American human gnathostomiasis in western blot assays using crude antigens prepared from <em>Gnathostoma... (Publications)
Gnathostomiasis is a zoonotic parasitosis endemic in many Asian and some Latin American countries. Most human infections are caused by Gnathostoma spinigerum in Asia and Gnathostoma binucleatum in the
Miltefosine for mucosal and complicated cutaneous old world leishmaniasis: a case series and review of the literature (Publications)
Complicated Old World cutaneous leishmaniasis (OWCL) and Old World mucosal leishmaniasis (OWML) constitute an indication for systemic treatment. To date, there no controlled clinical studies that comp
Dynamics of anemia in relation to parasitic infections, micronutrient status, and growing age in south-central Côte d'Ivoire (Publications)
Background. Parasitic diseases (e.g., malaria and helminthiases) exert enormous burdens on public health and social wellbeing. Moreover, parasitic infections are important causes of anemia in tropical
Insecticide resistance and its association with target-site mutations in natural populations of <em>Anopheles gambiae</em> from eastern Uganda (Publications)
Insecticide resistance in Anopheles gambiae threatens the success of malaria vector control programmes in sub-Saharan Africa. In order to manage insecticide resistance successfully, it is essential to
Plasma and exhaled breath condensate nitrite-nitrate level in relation to environmental exposures in adults in the EGEA study (Publications)
This study evaluated the associations between biological markers in the nitrate-nitrite-NO pathway and four environmental exposures among subjects examined in the second survey (2003-2007) of the Fren
IMP3 expression in lesions of the biliary tract: a marker for high-grade dysplasia and an independent prognostic factor in bile duct carcinomas (Publications)
The oncofetal protein IMP3 (insulin-like growth factor II mRNA binding protein 3) is expressed during embryogenesis and carcinogenesis. Various tumor types have been analyzed for IMP3 expression, whic
